[HTML][HTML] Chloride ion dysregulation in epileptogenic neuronal networks
SA Weiss - Neurobiology of Disease, 2023 - Elsevier
GABA is the major inhibitory neurotransmitter in the mature CNS. When GABA A receptors
are activated the membrane potential is driven towards hyperpolarization due to chloride …
are activated the membrane potential is driven towards hyperpolarization due to chloride …
Pathological and physiological high-frequency oscillations on electroencephalography in patients with epilepsy
High-frequency oscillations (HFOs) encompass ripples (80 Hz–200 Hz) and fast ripples (200
Hz–600 Hz), serving as a promising biomarker for localizing the epileptogenic zone in …
Hz–600 Hz), serving as a promising biomarker for localizing the epileptogenic zone in …
Sleep, oscillations, and epilepsy
Sleep and wake are defined through physiological and behavioral criteria and can be
typically separated into non‐rapid eye movement (NREM) sleep stages N1, N2, and N3 …
typically separated into non‐rapid eye movement (NREM) sleep stages N1, N2, and N3 …
[HTML][HTML] Mouse model of focal cortical dysplasia type II generates a wide spectrum of high-frequency activities
J Chvojka, N Prochazkova, M Rehorova… - Neurobiology of …, 2024 - Elsevier
High-frequency oscillations (HFOs) represent an electrographic biomarker of endogenous
epileptogenicity and seizure-generating tissue that proved clinically useful in presurgical …
epileptogenicity and seizure-generating tissue that proved clinically useful in presurgical …
Fast ripples reflect increased excitability that primes epileptiform spikes
The neuronal circuit disturbances that drive inter-ictal and ictal epileptiform discharges
remain elusive. Using a combination of extra-operative macro-electrode and micro-electrode …
remain elusive. Using a combination of extra-operative macro-electrode and micro-electrode …
Pathological neurons generate ripples at the UP‐DOWN transition disrupting information transfer
Objective To confirm and investigate why pathological high‐frequency oscillations (pHFOs),
including ripples (80–200 Hz) and fast ripples (200–600 Hz), are generated during the UP …
including ripples (80–200 Hz) and fast ripples (200–600 Hz), are generated during the UP …
[HTML][HTML] Graph theoretical measures of fast ripple networks improve the accuracy of post-operative seizure outcome prediction
Fast ripples (FR) are a biomarker of epileptogenic brain, but when larger portions of FR
generating regions are resected seizure freedom is not always achieved. To evaluate and …
generating regions are resected seizure freedom is not always achieved. To evaluate and …
Stimulation better targets fast‐ripple generating networks in super responders to the responsive neurostimulator system
How responsive neurostimulation (RNS) decreases seizure frequency is unclear.
Stimulation may alter epileptic networks during inter‐ictal epochs. Definitions of the epileptic …
Stimulation may alter epileptic networks during inter‐ictal epochs. Definitions of the epileptic …
[HTML][HTML] Widespread slow oscillations support interictal epileptiform discharge networks in focal epilepsy
Interictal epileptiform discharges (IEDs) often co-occur across spatially-separated cortical
regions, forming IED networks. However, the factors prompting IED propagation remain …
regions, forming IED networks. However, the factors prompting IED propagation remain …
The Role of High-Frequency Oscillation Networks in Managing Pharmacoresistant Epilepsy
Persons with pharmacoresistant epilepsy have a higher risk of mortality than those with
controlled seizures. Seizure control can be achieved with surgical removal or electrical …
controlled seizures. Seizure control can be achieved with surgical removal or electrical …