Introduction Malaria, a devastating febrile illness caused by protozoan parasites, sickened
247,000,000 people in 2021 and killed 619,000, mostly children and pregnant women in …

Infections and inflammation during pregnancy or early life can alter child neurodevelopment
and increase the risk for structural brain abnormalities and mental health disorders. There is …

Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …

Immunization strategies are part of routine pregnancy care to prevent infectious diseases in
the mother, the fetus, and the newborn. Maternal immunization recommendations followed …

Pregnant women attending first antenatal care (ANC) visits represent a promising malaria
surveillance target in Sub-Saharan Africa. We assessed the spatio-temporal relationship …

Malaria during pregnancy is a major global health problem caused by infection with
Plasmodium falciparum parasites. Severe effects arise from the accumulation of infected …

Prenatal maternal immunization is an effective tool to protect mothers and infants from poor
health outcomes due to infectious diseases. We provide an overview of the rationale for the …

VAR2CSA, a multidomain Plasmodium falciparum protein, mediates the adherence of
parasite-infected red blood cells to chondroitin 4-sulfate (C4S) in the placenta, contributing …

During Plasmodium falciparum infection in pregnancy, VAR2CSA is expressed on the
surface of infected erythrocytes (IEs) and mediates their sequestration in the placenta. As a …

While two Plasmodium falciparum circumsporozoite protein-based pre-erythrocytic vaccines
(PEV), RTS, S and R21, have been approved by the WHO, no blood-stage vaccine (BSV) or …