Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse
S Osmanagic-Myers, A Kiss… - The Journal of …, 2019 - Am Soc Clin Investig
Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disorder characterized
by accelerated cardiovascular disease with extensive fibrosis. It is caused by a mutation in …
by accelerated cardiovascular disease with extensive fibrosis. It is caused by a mutation in …
In vivo imaging with confirmation by histopathology for increased rigor and reproducibility in translational research: A review of examples, options, and resources
K Gabrielson, R Maronpot, S Monette… - ILAR …, 2018 - academic.oup.com
Preclinical noninvasive imaging can be an indispensable tool for studying animal models of
disease. In vivo imaging to assess anatomical, functional, and molecular features requires …
disease. In vivo imaging to assess anatomical, functional, and molecular features requires …
Cardioprotection in cardiovascular surgery
Since the invention of cardiopulmonary bypass, cardioprotective strategies have been
investigated to mitigate ischemic injury to the heart during aortic cross-clamping and …
investigated to mitigate ischemic injury to the heart during aortic cross-clamping and …
Tenascin-C promotes chronic pressure overload-induced cardiac dysfunction, hypertrophy and myocardial fibrosis
BK Podesser, M Kreibich, E Dzilic, D Santer… - Journal of …, 2018 - journals.lww.com
Aims: Left ventricular (LV) hypertrophy is characterized by cardiomyocyte hypertrophy and
interstitial fibrosis ultimately leading to increased myocardial stiffness and reduced …
interstitial fibrosis ultimately leading to increased myocardial stiffness and reduced …
Tenascin‐C aggravates ventricular dilatation and angiotensin‐converting enzyme activity after myocardial infarction in mice
D Santer, F Nagel, IF Gonçalves, C Kaun… - ESC Heart …, 2020 - Wiley Online Library
Abstract Aims Tenascin‐C (TN‐C) is suggested to be detrimental in cardiac remodelling
after myocardial infarction (MI). The aim of this study is to reveal the effects of TN‐C on …
after myocardial infarction (MI). The aim of this study is to reveal the effects of TN‐C on …
The impact of age on cardiac function and extracellular matrix component expression in adverse post-infarction remodeling in mice
F Nagel, D Santer, S Stojkovic, C Kaun… - Experimental …, 2019 - Elsevier
The aim of this study was to describe the potential associations of the expression of
matricellular components in adverse post-infarction remodeling of the geriatric heart. In male …
matricellular components in adverse post-infarction remodeling of the geriatric heart. In male …
Semi-minimal invasive method to induce myocardial infarction in rats and the assessment of cardiac function by an isolated working heart system
PM Pilz, M Lang, O Hamza, PL Szabo, M Inci… - JoVE (Journal of …, 2020 - jove.com
Myocardial infarction (MI) remains the main contributor to morbidity and mortality worldwide.
Therefore, research on this topic is mandatory. An easily and highly reproducible MI …
Therefore, research on this topic is mandatory. An easily and highly reproducible MI …
Tenascin-C influences vascular dysfunction after myocardial infarction in mice
L Weber - 2020 - phaidra.vetmeduni.ac.at
Hintergrund: Der Myokardinfarkt (MI) als fatale Folge einer koronaren Gefäßerkrankung ist
die häufigste Todesursache weltweit. Es konnte gezeigt werden, dass die Aktivierung des …
die häufigste Todesursache weltweit. Es konnte gezeigt werden, dass die Aktivierung des …