Transforming growth factor‐β (TGF‐β) superfamily signaling via their cognate receptors is
frequently modified by TGF‐β superfamily co‐receptors. Signaling through SMAD‐mediated …

Gastrointestinal nematodes (GINs) can be a major constraint and global challenge to the
sheep industry. These nematodes infect the small intestine and abomasum of grazing …

Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy owing to
relapse caused by resistance to chemotherapy. We previously reported that cluster of …

Cancer-associated fibroblasts (CAFs) are an integral component of the tumor
microenvironment (TME). Most CAFs shape the TME toward an immunosuppressive milieu …

In nasopharyngeal carcinoma (NPC), the TGF-β/Smad pathway genes are altered with
inactive TGF-β signal, but the mechanisms remain unclear. RNA-sequencing results showed …

Background: The progression of lung adenocarcinoma (LUAD) may be related to abnormal
fatty acid metabolism (FAM). The present study investigated the relationship between FAM …

Lung adenocarcinoma (LUAD) is the most common type of lung cancer and one of the
malignancies with the highest incidence rate and mortality worldwide. Hypoxia is a typical …

Drug resistance is a considerable obstacle to gastric cancer (GC) treatment. The current
work aimed to elucidate the functional mechanism of CD109 in 5‐fluorouracil (5‐FU) …

The necessity to accurately predict recurrence and clinical outcome in early stage colorectal
cancer (CRC) is critical to identify those patients who may benefit from adjuvant …

Background: T cell exhaustion (TEX) is an important immune escape mechanism, and an in-
depth understanding of it can help improve cancer immunotherapy. However, the prognostic …