Minimising the potential for metabolic activation in drug discovery

AS Kalgutkar, JR Soglia - Expert opinion on drug metabolism & …, 2005 - Taylor & Francis
Investigations into the role of bioactivation in the pathogenesis of xenobiotic-induced toxicity
have been a major area of research since the link between reactive metabolites and …

胺碘酮在心律失常治疗中的应用现状

金晓东, 刘锡强, 宋丽娜, 李继福 - 心血管病学进展, 2009 - cqvip.com
胺碘酮在心律失常治疗中的应用现状-[维普官方网站]-www.cqvip.com-维普网  我的维普 购物车
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Causality assessment of liver injury after chronic oral amiodarone intake

L Llanos, R Moreu, AM Peiró, S Pascual… - … and Drug Safety, 2009 - Wiley Online Library
Abstract Background/Aim The number of patients receiving amiodarone will increase in
future years. As clinically significant hepatotoxicity associated with oral amiodarone is …

胺碘酮致急性肝损伤一例

李莉, 杨俊, 丁家望, 杨简, 李书国, 童莉, 李松… - 中华心血管病杂志, 2008 - cqvip.com
患者男, 70 岁. 因“发作性胸闷, 胸痛, 心慌伴活动后气促10 年, 加重1d” 收治入院.
患者既往多次来我科住院, 诊断为冠心病, 心律失常[心房颤动(房颤)]. 否认高血压 …