Current developments in the synthesis of 4-chromanone-derived compounds
The chroman-4-one framework is a significant structural entity that belongs to the class of
oxygen-containing heterocycles. It acts as a major building block in a large class of …
oxygen-containing heterocycles. It acts as a major building block in a large class of …
Catalytic stereoselective multicomponent reactions for the synthesis of spiro derivatives: recent progress
Spiro derivatives are important scaffolding substances found in many natural products and
pharmaceuticals. In the last decade, numerous new approaches based on multicomponent …
pharmaceuticals. In the last decade, numerous new approaches based on multicomponent …
[HTML][HTML] Piperine supplementation in diet improves growth, feed efficiency, innate immunity, digestibility and disease resistance of Pacific white shrimp (Litopenaeus …
J Shin, KS Yun, BE Gunathilaka, M Hasanthi, D Ko… - Aquaculture …, 2023 - Elsevier
Piperine is a phytobiotic and a polyphenol-derived alkaloid compound extracted from the
pepper. We evaluated the effects of dietary piperine on growth, feed utilization, innate …
pepper. We evaluated the effects of dietary piperine on growth, feed utilization, innate …
Versatile Therapeutic Values of N‐Containing Heterocycles Benzimidazole, Piperazine and Piperidine Hybrids
Nitrogen‐containing benzimidazole, piperazine, and piperidine are significant
pharmacophores in medicinal chemistry and drug development. Many medications, lead …
pharmacophores in medicinal chemistry and drug development. Many medications, lead …
Rhodium (III)‐Catalyzed C7‐Spiroannulation of Indolines with Maleimides: Facile Access to Aza‐Spiromulticycles
J Zhao, C Pi, Y Wu, X Cui - Advanced Synthesis & Catalysis, 2024 - Wiley Online Library
Herein, we report a chemo‐and regioselective Rh‐catalyzed redox C7‐spiroannulation
reaction of N‐benzo [d] imidazole indolines with maleimides, resulting in a series of N …
reaction of N‐benzo [d] imidazole indolines with maleimides, resulting in a series of N …
Construction of 2-alkynyl aza-spiro [4, 5] indole scaffolds via sequential C–H activations for modular click chemistry libraries
J Zhang, M Wang, H Wang, H Xu, J Chen… - Chemical …, 2021 - pubs.rsc.org
Herein, we have developed a strategy of sequential C–H activations of indole to construct
novel 2-alkynyl aza-spiro [4, 5] indole scaffolds, which incorporated both alkyne and spiro …
novel 2-alkynyl aza-spiro [4, 5] indole scaffolds, which incorporated both alkyne and spiro …
Design, Synthesis and Biological Evaluation of Novel Spiro‐[Chroman‐2, 4′‐Piperidin]‐4‐One Analogs as Anti‐Tubercular Agents
S Chitti, A Nandikolla, YM Khetmalis… - Chemistry & …, 2022 - Wiley Online Library
A series of novel spiro‐[chromane‐2, 4′‐piperidin]‐4 (3H)‐one derivatives were designed,
synthesized and structures were confirmed by analytical methods, viz., 1H‐NMR, 13C‐NMR …
synthesized and structures were confirmed by analytical methods, viz., 1H‐NMR, 13C‐NMR …
Condensation reactions of dialkoxy-2-phenylchroman-4-ones with 1, 2-diamines: A method for the preparation of chromenoquinoxalines
H Watkins, G Lee, PHB Ouedraogo, CW Padgett… - Tetrahedron …, 2023 - Elsevier
Abstract Reactions of dialkoxy-2-phenylchroman-4-ones (2, 3-diethoxy-3-hydroxy-2-
phenylchroman-4-one (1) and 2, 3-dimethoxy-3-hydroxy-2-phenylchroman-4-one (2)) with …
phenylchroman-4-one (1) and 2, 3-dimethoxy-3-hydroxy-2-phenylchroman-4-one (2)) with …
A Review on Chemical and Biological Studies of 4-Chromanone Derivatives
MI Hegab - Russian Journal of Organic Chemistry, 2023 - Springer
The chroman-4-one skeleton is a remarkable structural system that belongs to oxygen-
containing heterocycles. It constitutes a major building block in a large class of medicinal …
containing heterocycles. It constitutes a major building block in a large class of medicinal …
Unexpected but prominent imines formation in Beckmann rearrangement of (spiro) pyranocoumarin oximes
IV Krasylov, VS Moskvina, VP Khilya - Tetrahedron Letters, 2023 - Elsevier
This paper presents the successful implementation of Beckmann rearrangement on a series
of (spiro) pyranocoumarin oximes in polyphosphoric acid (PPA) medium. The method …
of (spiro) pyranocoumarin oximes in polyphosphoric acid (PPA) medium. The method …