Uterine leiomyomas are one of the most common and yet understudied diseases in women.
These tumors, commonly known as fibroids, affect women mainly during their reproductive …

Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …

Background: The first objective of this review was to present, based on recent literature, the
most frequently applied medical options (oral contraceptive pills (OCPs) and progestogens) …

Uterine fibroids affect a wide cross-section of the population, with prevalence, symptom
severity, and overall disease burden generally higher among black women, likely due to …

Background Uterine fibroids are a common cause of heavy menstrual bleeding and pain.
Treatment with the combination of relugolix (an oral gonadotropin-releasing hormone …

Infertility is a disease of the reproductive system defined by the failure to achieve a clinical
pregnancy after 12 months or more of regular unprotected sexual intercourse. Uterine …

Background Uterine fibroids are hormone-responsive neoplasms that are associated with
heavy menstrual bleeding. Elagolix, an oral gonadotropin-releasing hormone antagonist …

Background Uterine fibroids are common non-cancerous neoplasm that cause heavy
menstrual bleeding and other signs. Linzagolix is an oral gonadotropin-releasing hormone …

Uterine myomas or fibroids are the most common benign female tumors of the reproductive
organs, associated with significant morbidity and quality of life impairment. Several …

BACKGROUND Stem cell research in the endometrium and myometrium from animal
models and humans has led to the identification of endometrial/myometrial stem cells and …