Cancer treatment has been always considered one of the most critical and vital themes of
clinical issues. Many approaches have been developed, depending on the type and the …

DNA vaccines offer a flexible and versatile platform to treat innumerable diseases due to the
ease of manipulating vaccine targets simply by altering the gene sequences encoded in the …

Gene therapy promises to revolutionize biomedicine and personalized medicine by
modulating or compensating the expression of abnormal genes. The biggest obstacle for …

Simultaneous drug and gene delivery to cancer cells has been introduced to provide
advantages of the synergistic effects of gene to sensitize the cancer cells to …

Nanoparticles have been widely used for many applications such as catalysis, biomedicine,
or self-healing. Core–shell nanoparticles are very promising for biomedical applications due …

Plasmid DNA molecules with unique loop structures have widespread bioapplications, in
many cases relying heavily on delivery vehicles to introduce them into cells and achieve …

The-state-of-art CRISPR/Cas9 is one of the most powerful among the approaches being
developed to rescue fundamental causes of gene-based inheritable diseases. Several …

An overview of the application of natural and synthetic, non-viral vectors for oligonucleotide
delivery into the lung is presented in this review, with a special focus on lung cancer. Due to …

Respiratory disorders are among the most important medical problems threatening human
life. The conventional therapeutics for respiratory disorders are hindered by insufficient drug …

Gene delivery for molecular-level therapeutics is regarded as a prospective remedial route
to cure human diseases by the medical community. The major challenge for delivering …