Serine-Threonine kinase CK2 supports malignant B-lymphocyte growth but its role in B-cell
development and activation is largely unknown. Here, we describe the first B-cell specific …

The protein kinase casein kinase 2 (CK2) exerts its influence on the metabolism of three
major cellular substances by phosphorylating essential protein molecules involved in …

The epigenetic silencing of tumor suppressor genes in myelodysplastic syndromes (MDS)
can potentially confer a growth advantage to individual cellular clones. Currently, the …

Background Protein kinase CK2 activity is implicated in the pathogenesis of various
hematological malignancies like Acute Myeloid Leukemia (AML) that remains challenging …

Casein kinase 2 (CK2) regulates a plethora of proteins with pivotal roles in solid and
hematological neoplasia. Particularly, in acute myeloid leukemia (AML) CK2 has been …

Simple Summary Acute Myeloid Leukemia is an aggressive disease with poor outcomes.
New targeted therapies that can boost the effects of currently used chemotherapy …

Introduction In classical Hodgkin lymphoma (cHL), the survival of neoplastic cells is
mediated by the activation of NF-κB, JAK/STAT and PI3K/Akt signaling pathways. CK2 is a …

Abstract Background Casein kinase II (CK2) is involved in multiple tumor-relevant signaling
pathways affecting proliferation and apoptosis. CK2 is frequently upregulated in acute B …

Background/Aims: Solamargine, one natural photochemical component from traditional
plants, has been shown to have anti-cancers properties. We previously showed that …

Protein kinase CK2, a member of the eukaryotic protein kinase superfamily, is associated
with cancer and other human pathologies and thus an attractive drug target. The indeno [1, 2 …