旨在从奶牛乳腺组织中分离原代乳腺上皮细胞(bovine mammary epithelial cells, BMECs)
并传代培养后探究其生物学特性. 本研究从屠宰场采集健康泌乳奶牛乳腺并采用改进的酶消化法 …

The Pea3 Ets transcription factor is overexpressed in breast tumors suggesting that it plays a
role in mammary oncogenesis. However, the normal biological function of Pea3 in the …

This study has utilised comparative functional genomics to exploit animal models with
extreme adaptation to lactation to identify candidate genes that specifically regulate protein …

Differentiation of the mammary gland during pregnancy and the first several days following
parturition is required for the establishment of a normal lactation. The expansion and …

Terminal differentiation of mammary tissue into a functional epithelium that synthesizes and
secretes milk occurs during pregnancy. The molecular mechanisms underlying this complex …

The protein tyrosine phosphatase receptor J, PTPRJ, is a tumor suppressor gene that has
been implicated in a range of cancers, including breast cancer, yet little is known about its …

Methods: Among 555 women enrolled in the Healthy Start study (2009–2014), we quantified
maternal serum concentrations of 5 PFAS during mid-to late-pregnancy (mean 27 weeks of …

Ovarian cells within the area of impending follicular rupture in the sheep exhibit evidence of
DNA fragmentation. Most cells undergo a degenerative process indicative of apoptosis and …

Since the discovery of physiologically-regulated prolactin (PRL) phosphorylation, one focus
of the laboratory has been an examination of the different functions of the unmodified and …

Background Tetraspanins are transmembrane proteins that serve as scaffolds for
multiprotein complexes containing, for example, integrins, growth factor receptors and matrix …