Prostate cancer has the highest prevalence of any nonskin cancer in the human body, with
similar likelihood of neoplastic foci found within the prostates of men around the world …

Hereditary prostate cancer, a newly described variant of prostate cancer, is distinguished by
early age at onset and autosomal dominant inheritance within families. 1 We review the …

Purpose: To review the current state of knowledge regarding risk factors for prostate cancer.
Data Sources: Analysis of the literature through the use of MEDLINE as well as identification …

OBJECTIVE To identify published studies quantifying familial prostate cancer risks in
relatives of prostate cancer cases and, by meta‐analysis, obtain more precise estimates of …

BACKGROUND Although narrative reviews have concluded that there is strong support for
familial clustering of prostate carcinoma, the association has never systematically been …

Practical and clinically focused, Abeloff's Clinical Oncology is a trusted medical reference
book designed to capture the latest scientific discoveries and their implications for cancer …

Malignant transformation of the prostate and progression of carcinoma appear to be the
consequence of a complex series of initiation and promotional events under genetic and …

Prostate cancer is the most frequent cancer among men in most developed countries, yet
little is known about its causes. Older age, African ancestry and a positive family history of …

Studies on familial aggregation of cancer may suggest an overall contribution of inherited
genes or a shared environment in the development of malignant disease. We performed a …

Increased risk of prostate cancer in men with a family history of the disease has been
observed consistently in epidemiologic studies. However, most studies have been confined …