Unbiased spatial proteomics with single-cell resolution in tissues

A Mund, AD Brunner, M Mann - Molecular Cell, 2022 - cell.com
Mass spectrometry (MS)-based proteomics has become a powerful technology to quantify
the entire complement of proteins in cells or tissues. Here, we review challenges and recent …

Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Spatially resolved mass spectrometry at the single cell: recent innovations in proteomics and metabolomics

MJ Taylor, JK Lukowski… - Journal of the American …, 2021 - ACS Publications
Biological systems are composed of heterogeneous populations of cells that
intercommunicate to form a functional living tissue. Biological function varies greatly across …

Common principles and best practices for engineering microbiomes

CE Lawson, WR Harcombe, R Hatzenpichler… - Nature Reviews …, 2019 - nature.com
Despite broad scientific interest in harnessing the power of Earth's microbiomes, knowledge
gaps hinder their efficient use for addressing urgent societal and environmental challenges …

Impact of impurities on water electrolysis: a review

H Becker, J Murawski, DV Shinde… - Sustainable Energy & …, 2023 - pubs.rsc.org
Low temperature water electrolysers such as Proton Exchange Membrane Water
Electrolysers (PEMWEs), Alkaline Water Electrolysers (AWEs), and Anion Exchange …

Raman microspectroscopy for microbiology

KS Lee, Z Landry, FC Pereira, M Wagner… - Nature Reviews …, 2021 - nature.com
Raman microspectroscopy offers microbiologists a rapid and non-destructive technique to
assess the chemical composition of individual live microorganisms in near real time. In this …

Advances in mass spectrometry based single-cell metabolomics

KD Duncan, J Fyrestam, I Lanekoff - Analyst, 2019 - pubs.rsc.org
Metabolomics has grown into a prominent field contributing to the molecular understanding
of complex biological processes in both health and disease. Furthermore, single-cells are …

Roadmap for focused ion beam technologies

K Höflich, G Hobler, FI Allen, T Wirtz, G Rius… - Applied Physics …, 2023 - pubs.aip.org
The focused ion beam (FIB) is a powerful tool for fabrication, modification, and
characterization of materials down to the nanoscale. Starting with the gallium FIB, which was …

Multimodal imaging mass spectrometry: next generation molecular mapping in biology and medicine

EK Neumann, KV Djambazova… - Journal of the …, 2020 - ACS Publications
Imaging mass spectrometry has become a mature molecular mapping technology that is
used for molecular discovery in many medical and biological systems. While powerful by …

Microbial ecology of the cryosphere (glacial and permafrost habitats): current knowledge

R Margesin, T Collins - Applied microbiology and biotechnology, 2019 - Springer
Microorganisms in cold ecosystems play a key ecological role in their natural habitats. Since
these ecosystems are especially sensitive to climate changes, as indicated by the worldwide …