Nonalcoholic fatty liver disease in adults: current concepts in etiology, outcomes, and management

T Marjot, A Moolla, JF Cobbold, L Hodson… - Endocrine …, 2020 - academic.oup.com
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of disease, extending from simple
steatosis to inflammation and fibrosis with a significant risk for the development of cirrhosis. It …

Therapeutic targets, novel drugs, and delivery systems for diabetes associated NAFLD and liver fibrosis

V Kumar, X Xin, J Ma, C Tan, N Osna… - Advanced drug delivery …, 2021 - Elsevier
Type 2 diabetes mellitus (T2DM) associated non-alcoholic fatty liver disease (NAFLD) is the
fourth-leading cause of death. Hyperglycemia induces various complications, including …

[HTML][HTML] Peroxisome proliferator-activated receptors and their novel ligands as candidates for the treatment of non-alcoholic fatty liver disease

A Fougerat, A Montagner, N Loiseau, H Guillou… - Cells, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a major health issue worldwide, frequently
associated with obesity and type 2 diabetes. Steatosis is the initial stage of the disease …

[HTML][HTML] Gut-pancreas-liver axis as a target for treatment of NAFLD/NASH

G Svegliati-Baroni, B Patrício, G Lioci… - International journal of …, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) represents the most common form of chronic liver
disease worldwide. Due to its association with obesity and diabetes and the fall in hepatitis …

Impact of fenofibrate on NAFLD/NASH: A genetic perspective

A Mahmoudi, T Jamialahmadi, TP Johnston… - Drug discovery today, 2022 - Elsevier
Highlights•NAFLD is highly prevalent and affects at least one-third of the global
population.•Currently, there is no drug to cure NAFLD.•Fenofibrate is a PPARα agonist with …

[HTML][HTML] Current therapeutical approaches targeting lipid metabolism in NAFLD

M Vitulo, E Gnodi, G Rosini, R Meneveri… - International Journal of …, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD, including nonalcoholic fatty liver (NAFL) and
nonalcoholic steatohepatitis (NASH)) is a high-prevalence disorder, affecting about 1 billion …

[HTML][HTML] Antidiabetic drugs in NAFLD: the accomplishment of two goals at once?

M Tacelli, C Celsa, B Magro, A Giannetti, G Pennisi… - Pharmaceuticals, 2018 - mdpi.com
Non-Alcoholic Fatty Liver Disease (NAFLD) is the most common cause of chronic liver
disease in Western countries, accounting for 20–30% of general population and reaching a …

[HTML][HTML] The role of anti-diabetic drugs in NAFLD. Have we found the Holy Grail? A narrative review

M Zachou, P Flevari, N Nasiri-Ansari… - European Journal of …, 2024 - Springer
Purpose Non-alcoholic fatty liver disease (NAFLD) has become a leading cause of liver
disease, affecting 30% of the global population. NAFLD prevalence is particularly high in …

[HTML][HTML] Liver-targeting drugs and their effect on blood glucose and hepatic lipids

A Gastaldelli, N Stefan, HU Häring - Diabetologia, 2021 - Springer
The global epidemic of non-alcoholic fatty liver disease (NAFLD) and steatohepatitis (NASH)
and the high prevalence among individuals with type 2 diabetes has attracted the attention …

MiR-21 and Tocilizumab interactions improve COVID-19 myocarditis outcomes

A Hossein Heydari, S Ghaffari, Z Khani… - Therapeutic …, 2023 - journals.sagepub.com
Background: Myocarditis is now one of the most fatal and morbid complications of COVID-
19. Many scientists have recently concentrated on this problem. Objectives: This study …