The immunomodulatory properties of amniotic cells: the two sides of the coin

M Magatti, E Vertua, A Cargnoni, A Silini… - Cell …, 2018 - journals.sagepub.com
Among the many cell types useful in developing therapeutic treatments, human amniotic
cells from placenta have been proposed as valid candidates. Both human amniotic epithelial …

Amniotic membrane mesenchymal cells-derived factors skew T cell polarization toward Treg and downregulate Th1 and Th17 cells subsets

S Pianta, P Bonassi Signoroni, I Muradore… - Stem Cell Reviews and …, 2015 - Springer
We previously demonstrated that cells derived from the mesenchymal layer of the human
amniotic membrane (hAMSC) and their conditioned medium (CM-hAMSC) modulate …

The truth is out there: biological features and clinical indications of Extracellular vesicles from human perinatal stem cells

E Russo, G Alberti, S Corrao, CV Borlongan, V Miceli… - Cells, 2023 - mdpi.com
The potential of perinatal tissues to provide cellular populations to be used in different
applications of regenerative medicine is well established. Recently, the efforts of …

Mesenchymal stem cells: from identification and characterization to clinical applications

M Alvarez-Viejo, KH Haider - Handbook of stem cell therapy, 2022 - Springer
Since Friedenstein and co-workers first reported bone marrow-derived mesenchymal stem
cells (MSCs) during the early 1970s, several researchers have focused on their biology and …

Amniotic membrane-derived stem cells: immunomodulatory properties and potential clinical application

CL Insausti, M Blanquer… - Stem Cells and …, 2014 - Taylor & Francis
Epithelial and mesenchymal cells isolated from the amniotic membrane (AM) possess stem
cell characteristics, differentiation potential toward lineages of different germ layers, and …

Origin of stem cells in organogenesis

JMW Slack - Science, 2008 - science.org
The development of individual organs in animal embryos involves the formation of tissue-
specific stem cells that sustain cell renewal of their own tissue for the lifetime of the …

[HTML][HTML] In situ-formed adhesive hyaluronic acid hydrogel with prolonged amnion-derived conditioned medium release for diabetic wound repair

Y Zhang, Y Zheng, F Shu, R Zhou, B Bao, S Xiao… - Carbohydrate …, 2022 - Elsevier
Hydrogels have long been used for encapsulating stem cell-derived conditioned mediums to
achieve skin regeneration after wounding. However, inappropriate mechanical strength, low …

Placental mesenchymal stromal cells as an alternative tool for therapeutic angiogenesis

SA Mathew, C Naik, PA Cahill, RR Bhonde - Cellular and Molecular Life …, 2020 - Springer
Dysregulation of angiogenesis is a phenomenon observed in several disorders such as
diabetic foot, critical limb ischemia and myocardial infarction. Mesenchymal stromal cells …

Mesenchymal stromal cells from fetal and maternal placenta possess key similarities and differences: potential implications for their applications in regenerative …

A Papait, E Vertua, M Magatti, S Ceccariglia… - Cells, 2020 - mdpi.com
Placenta-derived mesenchymal stromal cells (MSC) have attracted more attention for their
immune modulatory properties and poor immunogenicity, which makes them suitable for …

Applications of human amniotic membrane for tissue engineering

M Fénelon, S Catros, C Meyer, JC Fricain, L Obert… - Membranes, 2021 - mdpi.com
An important component of tissue engineering (TE) is the supporting matrix upon which cells
and tissues grow, also known as the scaffold. Scaffolds must easily integrate with host tissue …