Thiazolidine-2, 4-diones: Progress towards multifarious applications
VS Jain, DK Vora, CS Ramaa - Bioorganic & medicinal chemistry, 2013 - Elsevier
The promising activity shown by compounds containing thiazolidine-2, 4-dione nucleus in
numerous categories such as anti-hyperglycaemics, aldose reductase inhibitors, anti …
numerous categories such as anti-hyperglycaemics, aldose reductase inhibitors, anti …
[HTML][HTML] Diabetes and the abdominal aortic aneurysm
S Shantikumar, R Ajjan, KE Porter, DJA Scott - European Journal of …, 2010 - Elsevier
OBJECTIVE: The aim of this review is to delineate the association between abdominal aortic
aneurysms (AAAs) and diabetes mellitus. Mechanisms for the underlying association are …
aneurysms (AAAs) and diabetes mellitus. Mechanisms for the underlying association are …
[HTML][HTML] Peroxisome proliferator-activated receptor (PPAR) gamma in cardiovascular disorders and cardiovascular surgery
EA Ivanova, A Parolari, V Myasoedova… - Journal of …, 2015 - Elsevier
Peroxisome proliferation-activated receptor gamma (PPARγ) is a nuclear receptor regulating
transcription of several genes involved mainly in fatty acid and energy metabolism. PPARγ …
transcription of several genes involved mainly in fatty acid and energy metabolism. PPARγ …
Peroxisome proliferator-activated receptor (PPAR) gamma agonists as therapeutic agents for cardiovascular disorders: focus on atherosclerosis
EA Ivanova, VA Myasoedova… - Current …, 2017 - ingentaconnect.com
Peroxisome proliferation-activated receptors (PPARs) are ligand-activated transcription
factors that mainly regulate genes responsible for fatty acid (FA) and energy metabolism …
factors that mainly regulate genes responsible for fatty acid (FA) and energy metabolism …
Angiotensin receptor blockers: a panacea for Marfan syndrome and related disorders?
BL Loeys - Drug discovery today, 2015 - Elsevier
Highlights•Study of Marfan mouse models revealed a key role for TGFβ signaling in the
pathogenesis of aortic aneurysm.•Canonical and noncanonical TGFβ signaling play parts in …
pathogenesis of aortic aneurysm.•Canonical and noncanonical TGFβ signaling play parts in …
[HTML][HTML] Effect of the Association of Fixed Oils from Abelmoschus esculentus (L.) Moench, Euterpe oleracea Martius, Bixa orellana Linné and Chronic SM® on …
PF Sales, AL Nascimento, FC Pinheiro, AKM Alberto… - Molecules, 2023 - mdpi.com
Dyslipidemia presents high levels of serum cholesterol and is characterized as a risk factor
for cardiovascular diseases, especially for the development of atherosclerosis. E. oleracea …
for cardiovascular diseases, especially for the development of atherosclerosis. E. oleracea …
Association of diabetes mellitus with presence, expansion, and rupture of abdominal aortic aneurysm:“Curiouser and curiouser!” cried ALICE
H Takagi, TU for the ALICE - Seminars in Vascular Surgery, 2016 - Elsevier
Both coronary artery and peripheral artery disease are representative atherosclerotic
diseases that are positively associated with presence of abdominal aortic aneurysm (AAA) …
diseases that are positively associated with presence of abdominal aortic aneurysm (AAA) …
[HTML][HTML] Decreased nuclear ascorbate accumulation accompanied with altered genomic methylation pattern in fibroblasts from arterial tortuosity syndrome patients
Ascorbate requiring Fe 2+/2-oxoglutarate-dependent dioxygenases located in the
nucleoplasm have been shown to participate in epigenetic regulation of gene expression via …
nucleoplasm have been shown to participate in epigenetic regulation of gene expression via …
TGF-beta1 is associated with the progression of intracranial deep white matter lesions: a pilot study with 5 years of magnetic resonance imaging follow-up
N Kuriyama, T Mizuno, M Kita, K Yamada… - Neurological …, 2014 - Taylor & Francis
Objectives: Elevated expression of transforming growth factor (TGF)-beta1 has been
reported in hereditary cerebral small-vessel (HCSV) disease. The aim of this study was to …
reported in hereditary cerebral small-vessel (HCSV) disease. The aim of this study was to …
Preventing the aortic complications of Marfan syndrome: a case‐example of translational genomic medicine
A Li‐Wan‐Po, B Loeys, P Farndon… - British journal of …, 2011 - Wiley Online Library
The translational path from pharmacological insight to effective therapy can be a long one.
We aim to describe the management of Marfan syndrome as a case‐example of how …
We aim to describe the management of Marfan syndrome as a case‐example of how …