Polyphenols and their impact on the prevention of neurodegenerative diseases and development

I Grabska-Kobyłecka, P Szpakowski, A Król… - Nutrients, 2023 - mdpi.com
It is well known that neurodegenerative diseases' development and progression are
accelerated due to oxidative stress and inflammation, which result in impairment of …

Flavonoids: Potential candidates for the treatment of neurodegenerative disorders

S Devi, V Kumar, SK Singh, AK Dubey, JJ Kim - Biomedicines, 2021 - mdpi.com
Neurodegenerative disorders, such as Parkinson's disease (PD), Alzheimer's disease (AD),
Amyotrophic lateral sclerosis (ALS), and Huntington's disease (HD), are the most concerning …

Neuroprotective potentials of flavonoids: Experimental studies and mechanisms of action

P Bellavite - Antioxidants, 2023 - mdpi.com
Neurological and neurodegenerative diseases, particularly those related to aging, are on
the rise, but drug therapies are rarely curative. Functional disorders and the organic …

Flavonoids as a natural enhancer of neuroplasticity—An overview of the mechanism of neurorestorative action

N Cichon, J Saluk-Bijak, L Gorniak, L Przyslo, M Bijak - Antioxidants, 2020 - mdpi.com
Neuroplasticity is a complex physiological process occurring in the brain for its entire life.
However, it is of particular importance in the case of central nervous system (CNS) …

Metabolic syndrome, cognitive impairment and the role of diet: a narrative review

M Kouvari, NM D'cunha, N Travica, D Sergi, M Zec… - Nutrients, 2022 - mdpi.com
Background: This narrative review presents the association between metabolic syndrome
(MetS), along with its components, and cognition-related disorders, as well as the potential …

Dietary (Poly) phenols and Cognitive Decline: A Systematic Review and Meta‐Analysis of Observational Studies

J Godos, A Micek, P Mena, D Del Rio… - Molecular Nutrition & …, 2024 - Wiley Online Library
Scope This study aims to systematically review observational studies investigating the
relation between dietary (poly) phenol consumption and various cognitive outcomes …

Insights into the pharmacological effects of flavonoids: the systematic review of computer modeling

A Taldaev, R Terekhov, I Nikitin, A Zhevlakova… - International Journal of …, 2022 - mdpi.com
Computer modeling is a method that is widely used in scientific investigations to predict the
biological activity, toxicity, pharmacokinetics, and synthesis strategy of compounds based on …

The neuromodulatory effects of flavonoids and gut Microbiota through the gut-brain axis

H Wang, T Zhao, Z Liu, Danzengquzhen… - Frontiers in Cellular …, 2023 - frontiersin.org
Recent investigations show that dietary consumption of flavonoids could potentially confer
neuroprotective effects through a variety of direct and indirect mechanisms. Numerous …

Zebrafish: A model deciphering the impact of flavonoids on neurodegenerative disorders

K Mhalhel, M Sicari, L Pansera, J Chen, M Levanti… - Cells, 2023 - mdpi.com
Over the past century, advances in biotechnology, biochemistry, and pharmacognosy have
spotlighted flavonoids, polyphenolic secondary metabolites that have the ability to modulate …

Potential In Vitro Inhibition of Selected Plant Extracts against SARS-CoV-2 Chymotripsin-Like Protease (3CLPro) Activity

C Guijarro-Real, M Plazas, A Rodríguez-Burruezo… - Foods, 2021 - mdpi.com
Antiviral treatments inhibiting Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) replication may represent a strategy complementary to vaccination to fight the ongoing …