Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes

P Pal, JM Fox, DW Hawman, YJS Huang… - Journal of …, 2014 - Am Soc Microbiol
Chikungunya virus (CHIKV) is a reemerging mosquito-transmitted alphavirus that causes
epidemics of debilitating polyarthritis in humans. A prior study identified two anti-CHIKV …

[HTML][HTML] Seroprevalence of chikungunya virus after its emergence in Brazil

JP Dias, NC Maria da Conceição… - Emerging infectious …, 2018 - ncbi.nlm.nih.gov
Chikungunya has had a substantial impact on public health because of the magnitude of its
epidemics and its highly debilitating symptoms. We estimated the seroprevalence …

Recomendações da Sociedade Brasileira de Reumatologia para diagnóstico e tratamento da febre chikungunya. Parte 1-Diagnóstico e situações especiais

CDL Marques, ALBP Duarte, A Ranzolin… - Revista Brasileira de …, 2017 - SciELO Brasil
Chikungunya fever has become a relevant public health problem in countries where
epidemics occur. Until 2013, only imported cases occurred in the Americas, but in October of …

Correlation of plasma viral loads and presence of Chikungunya IgM antibodies with cytokine/chemokine levels during acute Chikungunya virus infection

V Reddy, RS Mani, A Desai… - Journal of medical …, 2014 - Wiley Online Library
Chikungunya (CHIKV) is an emerging arboviral infection of public health concern in India
contributing to widespread morbidity. The precise molecular events occurring early in the …

Chikungunya fever: a threat to global public health

RNC Moizéis, TAAM Fernandes… - Pathogens and global …, 2018 - Taylor & Francis
Chikungunya fever is an emerging arbovirus infection, representing a serious public health
problem. Its etiological agent is the Chikungunya virus (CHIKV). Transmission of this virus is …

Osteoclastogenesis induced by CHIKV-infected fibroblast-like synoviocytes: a possible interplay between synoviocytes and monocytes/macrophages in CHIKV …

W Phuklia, J Kasisith, N Modhiran, E Rodpai… - Virus research, 2013 - Elsevier
Fibroblast-like synoviocytes are known to migrate from joint to joint and are proposed to be
one of the key players in the inflammatory cascade amplification in rheumatoid arthritis …

Chikungunya Virus Evades Antiviral CD8+ T Cell Responses To Establish Persistent Infection in Joint-Associated Tissues

BJ Davenport, C Bullock, MK McCarthy… - Journal of …, 2020 - Am Soc Microbiol
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes explosive
epidemics of a febrile illness characterized by debilitating arthralgia and arthritis that can …

Chikungunya: vision of the pain clinician

APCR Castro, RA Lima, JS Nascimento - Revista Dor, 2016 - SciELO Brasil
ABSTRACT BACKGROUND AND OBJECTIVES: Chikungunya is a viral disease of tropical
distribution which affects individuals in different countries of the world and is associated to …

Disease resolution in Chikungunya—what decides the outcome?

P Srivastava, A Kumar, A Hasan, D Mehta… - Frontiers in …, 2020 - frontiersin.org
Chikungunya disease (CHIKD) is a viral infection caused by an alphavirus, chikungunya
virus (CHIKV), and triggers large outbreaks leading to epidemics. Despite the low mortality …

Novel lesions of bones and joints associated with chikungunya virus infection in two mouse models of disease: new insights into disease pathogenesis

BA Goupil, MA McNulty, MJ Martin, MK McCracken… - PloS one, 2016 - journals.plos.org
Chikungunya virus is an arbovirus spread predominantly by Aedes aegypti and Ae.
albopictus mosquitoes, and causes debilitating arthralgia and arthritis. While these are …