[HTML][HTML] New trends in the practical use of isoquinoline alkaloids as potential drugs applicated in infectious and non-infectious diseases
T Tuzimski, A Petruczynik - Biomedicine & Pharmacotherapy, 2023 - Elsevier
In the last years, traditional natural products have been the center of attention for the
scientific community and exploration of their therapeutic abilities is proceeding permanently …
scientific community and exploration of their therapeutic abilities is proceeding permanently …
Screening of potential inhibitors against structural proteins from Monkeypox and related viruses of Poxviridae family via docking and molecular dynamics simulation
Monkeypox virus (MPXV) is an orthopoxvirus which causes zoonotic infection in humans.
Even though sporadic cases of this infection are limited to the African continent, but if the …
Even though sporadic cases of this infection are limited to the African continent, but if the …
Promising Potential of Curcumin and Related Compounds for Antiviral Drug Discovery
Viruses are acellular, microscopic, and mobile particles containing genetic particles, either
DNA/RNA strands as nucleoproteins, responsible for 69, 53,743 deaths till the year 2023 …
DNA/RNA strands as nucleoproteins, responsible for 69, 53,743 deaths till the year 2023 …
Identifying plant-derived antiviral alkaloids as dual inhibitors of SARS-CoV-2 main protease and spike glycoprotein through computational screening
COVID-19 is currently considered the ninth-deadliest pandemic, spreading through direct or
indirect contact with infected individuals. It has imposed a consistent strain on both the …
indirect contact with infected individuals. It has imposed a consistent strain on both the …
Diastereoselective Synthesis of (–)-6, 7-Dimethoxy-1, 2, 3, 4-tetrahydroisoquinoline-1-carboxylic Acid via Morpholinone Derivatives
M Chrzanowska, A Grajewska, MD Rozwadowska - Molecules, 2023 - mdpi.com
A simple and convenient synthesis of (–)-6, 7-dimethoxy-1, 2, 3, 4-tetrahydroisoquinoline-1-
carboxylic acid is described, applying a combination of two synthetic methods: the Petasis …
carboxylic acid is described, applying a combination of two synthetic methods: the Petasis …
[HTML][HTML] Therapeutic Potential of 1-(2-Chlorophenyl)-6, 7-dimethoxy-3-methyl-3, 4-dihydroisoquinoline
The synthesized compound 1-(2-chlorophenyl) 6-7-dimethoxy-3-methyl-3, 4-
dihydroisoquinoline (DIQ) was investigated as a biological agent. Its potential to affect …
dihydroisoquinoline (DIQ) was investigated as a biological agent. Its potential to affect …
In Silico Evaluation of 1‐Aminoisoquinoline Derivatives against Dengue Virus: Greener Access via a Sonochemical Method
DE Prasada Rao, M Bhuvan Tej, MD Raju… - …, 2024 - Wiley Online Library
The reported antiviral properties of isoquinolines including that of berberine against dengue
virus prompted us exploring a series of 1‐aminoisoquinoline derivatives against RdRp and …
virus prompted us exploring a series of 1‐aminoisoquinoline derivatives against RdRp and …
Synthesis and cytotoxic activity of some (+)-salsolidine derivatives
A Koval'skaya, A Gil'mutdinov, A Lobov… - Natural Product …, 2023 - Taylor & Francis
On the basis of typical for secondary amino group reactions a number of derivatives of
alkaloid (+)-salsolidine was synthesised. Cytotoxic properties of obtained compounds …
alkaloid (+)-salsolidine was synthesised. Cytotoxic properties of obtained compounds …