M2 macrophages-derived exosomal miRNA-23a-3p promotes the progression of oral squamous cell carcinoma by targeting PTEN

J Li, Y Bao, S Peng, C Jiang, L Zhu, S Zou… - Current Issues in …, 2023 - mdpi.com
Exosomes from tumor cells and immune cells regulate the tumor microenvironment through
the biomolecules or microRNAs (miRNAs) they carry. This research aims to investigate the …

Genomic analysis of waterpipe smoke-induced lung tumor autophagy and plasticity

RF Zaarour, M Sharda, B Azakir… - International Journal of …, 2022 - mdpi.com
The role of autophagy in lung cancer cells exposed to waterpipe smoke (WPS) is not known.
Because of the important role of autophagy in tumor resistance and progression, we …

Cuproptosis/OXPHOS tendency prediction of prognosis and immune microenvironment of esophageal squamous cell carcinoma: Bioinformatics analysis and …

L Li, H Cheng, L Gong, Y Huang, J Yang, Q Yan, S Dai… - Gene, 2024 - Elsevier
Background Cuproptosis is a newly discovered cell death mechanism that relies on
mitochondrial respiration, for which oxidative phosphorylation (OXPHOS) is an essential …

A perspective on tumor radiation resistance following high-LET radiation treatment

YS Rajpurohit, DK Sharma, M Lal, I Soni - Journal of Cancer Research …, 2024 - Springer
High-linear energy transfer (LET) radiation is a promising alternative to conventional low-
LET radiation for therapeutic gain against cancer owing to its ability to induce complex and …

miR‐450b promotes cell migration and invasion by inhibiting SERPINB2 in oral squamous cell carcinoma

X Wang, X Nie, G Xu, J Gao, B Wang, J Yang… - Oral …, 2024 - Wiley Online Library
Abstract Objective microRNA‐450b (miR‐450b) plays an important role in cancer
progression; however, its function in oral squamous cell carcinoma (OSCC) remains largely …

Systematic identification of key functional modules and genes in esophageal cancer

R Wu, H Zhuang, YK Mei, JY Sun, T Dong… - Cancer Cell …, 2021 - Springer
Background Esophageal cancer is associated with high incidence and mortality worldwide.
Differential expression genes (DEGs) and weighted gene co-expression network analysis …

Spatial heterogeneity and Immune infiltration of cellular lysosomal pathways reveals a new blueprint for tumor heterogeneity in esophageal cancer

J Wei, XM Wu, S Wang, S Liu, X Gao - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Esophageal squamous cell carcinoma (ESCC) is a common Malignant tumor of
digestive tract which have a potential association with lysosomal pathway. The purpose of …

NUPR1 contributes to activate TFE3-dependent autophagy leading to cervical cancer proliferation

X Wang, K Wang, X Wang - Heliyon, 2024 - cell.com
Cervical cancer is a malignant tumor that occurs in the cervix of women and endangers their
lives. In this study, we aimed to assess the roles of NUPR1 and TFE3 in cervical cancer. The …

Targeting ENPP1 depletion may be a promising therapeutic strategy for treating oral squamous cell carcinoma via cytotoxic autophagy‐related apoptosis

C Ma, J Zhao, L Zhou, C Jia, Y Shi, X Li… - The FASEB …, 2024 - Wiley Online Library
ENPP1 depletion closely related with modulation immunotherapy of several types of cancer.
However, the role of ENPP1 correlation with autophagy in oral squamous cell carcinoma …

Epithelial PD‐L1 expression at tumor front predicts overall survival in a cohort of oral squamous cell carcinomas from Sudan

NM Gaafar, TAH Osman, M Elsheikh… - Clinical and …, 2022 - Wiley Online Library
Background We recently described the tumor immune microenvironment (TIME) in oral
squamous cell carcinomas (OSCC) from Sudan by assessing the core of the lesions …