Hepatocellular carcinoma (HCC) is an aggressive disease with a poor clinical outcome. The
cancer stem cell (CSC) model states that tumour growth is powered by a subset of tumour …

Hepatocellular carcinoma (HCC) is a significant cause of cancer-related mortality owing to
resistance to traditional treatments and tumor recurrence after therapy, which leads to poor …

Abstract CD44/CD24 and ALDH1 are widely used cancer stem cell (CSC) markers in breast
cancer. However, their expression is not always consistent even in the same subtype of …

Since their identification in 1994, cancer stem cells (CSCs) have been objects of intensive
study. Their properties and mechanisms of formation have become a major focus of current …

Background CD90+ liver cancer cells have been described as cancer stem-cell-like (CSC),
displaying aggressive and metastatic phenotype. Using two different in vitro models, already …

Liver cancer is an aggressive disease with a poor outcome. Several hepatic stem/progenitor
markers are useful for isolating a subset of liver cells with stem cell features, known as …

Liver cancer is an often fatal malignant tumor with a high recurrence rate and
chemoresistance. The major malignant phenotypes of cancer, including recurrence …

There is increasing evidence that malignant tumors are initiated and maintained by a sub-
population of tumor cells that have similar biological properties to normal adult stem cells …

Cancer stem cells (CSCs) are generally dormant or slowly cycling tumor cells that have the
ability to reconstitute tumors. They are thought to be involved in tumor resistance to …

The poor outcome of patients with non-surgically removable advanced hepatocellular
carcinoma (HCC), the most frequent type of primary liver cancer, is mainly due to the high …