Iron is an important metal element involved in the regulation of male reproductive functions
and has dual effects on testicular tissue. A moderate iron content is necessary to maintain …

Ferroptosis, a regulated form of cell death, is characterized by iron-dependent lipid
peroxidation leading to oxidative damage to cell membranes. Cell sensitivity to ferroptosis is …

STUDY QUESTION What is the mechanism behind cryoinjury in human sperm, particularly
concerning the interplay between reactive oxygen species (ROS) and autophagy, and how …

Environmental methylmercury (MeHg) exposure has gained global attention owing to its
serious health hazards, especially neurotoxicity. Ferroptosis is a novel form of programmed …

L-Carnitine, a natural antioxidant found in mammals, plays a crucial role in the transport of
long-chain fatty acids across the inner mitochondrial membrane. It is used as a nutritional …

Infertility represents a significant global health challenge, affecting more than 12% of
couples worldwide, and most cases of infertility are caused by male factors. Several …

Ethnopharmacological relevance Tripterygium wilfordii polyglycoside tablet (TWP), a
traditional Chinese medicine preparation, has multiple pharmacological properties …

Ferroptosis is a type of programmed cell death mediated by iron-dependent lipid
peroxidation that leads to excessive lipid peroxidation in different cells. Ferroptosis is distinct …

Busulfan, a bifunctional alkylated chemotherapeutic agent, has male reproductive toxicity
and induce oligospermia, which is associated with ferroptosis. However, the specific target …

Oligoasthenoteratozoospermia (OAT) decreases male fertility, seriously affecting the
production of offspring. This study clarified the preventive impact of different moxibustion …