[HTML][HTML] Discovery of 42 genome-wide significant loci associated with dyslexia

C Doust, P Fontanillas, E Eising, SD Gordon, Z Wang… - Nature …, 2022 - nature.com
Reading and writing are crucial life skills but roughly one in ten children are affected by
dyslexia, which can persist into adulthood. Family studies of dyslexia suggest heritability up …

[HTML][HTML] The polygenic nature and complex genetic architecture of specific learning disorder

M Georgitsi, I Dermitzakis, E Soumelidou, E Bonti - Brain sciences, 2021 - mdpi.com
Specific Learning Disorder (SLD) is a multifactorial, neurodevelopmental disorder which
may involve persistent difficulties in reading (dyslexia), written expression and/or …

[PDF][PDF] Human microglia maturation is underpinned by specific gene regulatory networks

CZ Han, RZ Li, E Hansen, S Trescott, BR Fixsen… - Immunity, 2023 - cell.com
Microglia phenotypes are highly regulated by the brain environment, but the transcriptional
networks that specify the maturation of human microglia are poorly understood. Here, we …

[HTML][HTML] Disco interacting protein 2 homolog A (DIP2A): A key component in the regulation of brain disorders

B Zhang, X Zhang, M Omorou, K Zhao, Y Ruan… - Biomedicine & …, 2023 - Elsevier
Abstract Disco Interacting Protein 2 Homolog A (DIP2A) is expressed throughout the body
and abundantly expressed in the brain tissue. It is activated by Follistatin-like 1 (FSTL1) …

Research studies on dyslexia: Participant inclusion and exclusion criteria

JA Lopes, C Gomes, CR Oliveira… - European Journal of …, 2020 - Taylor & Francis
Dyslexia is a term widely used to describe reading characterised by problems with the fluent
and accurate letter or word recognition. Nevertheless, there is no consensus about the …

The association of dyslexia and developmental speech and language disorder candidate genes with reading and language abilities in adults

C Doust, SD Gordon, N Garden, SE Fisher… - Twin Research and …, 2020 - cambridge.org
Reading and language abilities are critical for educational achievement and success in
adulthood. Variation in these traits is highly heritable, but the underlying genetic architecture …

[HTML][HTML] Identification of phonology-related genes and functional characterization of Broca's and Wernicke's regions in language and learning disorders

N Unger, S Heim, DI Hilger, S Bludau… - Frontiers in …, 2021 - frontiersin.org
Impaired phonological processing is a leading symptom of multifactorial language and
learning disorders suggesting a common biological basis. Here we evaluated studies of …

[HTML][HTML] Specific learning disorders: variation analysis of 15 candidate genes in 9 multiplex families

F Calì, FD Di Blasi, E Avola, M Vinci, A Musumeci… - Medicina, 2023 - mdpi.com
Background and Objectives: Specific Learning Disorder (SLD) is a complex neurobiological
disorder characterized by a persistent difficult in reading (dyslexia), written expression …

The role of genetic factors in reading and its development across languages and writing systems

EL Grigorenko - Scientific Studies of Reading, 2022 - Taylor & Francis
This mini-review attempts to provide a capsule overview of the role of genetic factors in
reading and its development across languages and writing systems. The review is …

[HTML][HTML] Developmental Dyslexia: Insights from EEG-Based Findings and Molecular Signatures—A Pilot Study

D Theodoridou, CO Tsiantis, AM Vlaikou, V Chondrou… - Brain Sciences, 2024 - mdpi.com
Developmental dyslexia (DD) is a learning disorder. Although risk genes have been
identified, environmental factors, and particularly stress arising from constant difficulties …