T lymphocytes with~/~ receptors recognize antigen in association with the polymorphic
products of the class I and class II loci of the major histocompatibility complex (MHC). This …

Publisher Summary This chapter provides evidence that indicates a potential role for
superantigens in the pathogenesis of several human diseases. The term “superantigen” was …

Objective: To examine possible risk factors for relapse, including chronic nasal carriage of
Staphylococcus aureus and serial antineutrophil cytoplasmic antibody (ANCA) …

The structure of a bacterial superantigen, Staphylococcus aureus enterotoxin B, bound to a
human class II histocompatibility complex molecule (HLA-DR1) has been determined by X …

Publisher Summary This chapter focuses on two sets of molecules involved in the
proliferation and differentiation of highly purified human B lymphocytes: the molecules …

The three-dimensional structure of a Staphylococcus aureus superantigen, toxic shock
syndrome toxin-1 (TSST-1), complexed with a human class II major histocompatibility …

The recent discovery of the mode of interaction between a group of microbial proteins known
as superantigens and the immune system has opened a wide area of investigation into the …

Staphylococcus aureus is a facultative, Gram-positive coccus well known for its disease-
causing capabilities. In particular, methicillin and vancomycin resistant strains of S. aureus …

The superantigen staphylococcal enterotoxin A (SEA) binds to major histocompatibility
complex (MHC) class II molecules at two sites on either side of the peptide groove. Two …

The three-dimensional structure of the complex between a T cell receptor (TCR) β chain
(mouse Vβ8. 2Jβ2. 1Cβ1) and the superantigen (SAG) staphylococcal enterotoxin C3 …