Non-canonical WNT signalling in cardiovascular disease: mechanisms and therapeutic implications
I Akoumianakis, M Polkinghorne… - Nature Reviews …, 2022 - nature.com
WNT signalling comprises a diverse spectrum of receptor-mediated pathways activated by a
large family of WNT ligands and influencing fundamental biological processes. WNT …
large family of WNT ligands and influencing fundamental biological processes. WNT …
WNT signaling in melanoma
A Gajos-Michniewicz, M Czyz - International journal of molecular sciences, 2020 - mdpi.com
WNT-signaling controls important cellular processes throughout embryonic development
and adult life, so any deregulation of this signaling can result in a wide range of pathologies …
and adult life, so any deregulation of this signaling can result in a wide range of pathologies …
Molecular mechanisms of adipogenesis: the anti-adipogenic role of AMP-activated protein kinase
Obesity is now a widespread disorder, and its prevalence has become a critical concern
worldwide, due to its association with common co-morbidities like cancer, cardiovascular …
worldwide, due to its association with common co-morbidities like cancer, cardiovascular …
Association between obesity, inflammation and insulin resistance: Insights into signaling pathways and therapeutic interventions
Obesity, a metabolic disorder, is becoming a worldwide epidemic that predominantly
increases the risk for various diseases including metabolic inflammation, insulin resistance …
increases the risk for various diseases including metabolic inflammation, insulin resistance …
Running against the Wnt: How Wnt/β-catenin suppresses adipogenesis
TJJ De Winter, R Nusse - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs) give rise to adipocytes, osteocytes, and chondrocytes and
reside in various tissues, including bone marrow and adipose tissue. The differentiation …
reside in various tissues, including bone marrow and adipose tissue. The differentiation …
Inflammation and Wnt signaling: target for immunomodulatory therapy?
I Jridi, K Canté-Barrett, K Pike-Overzet… - Frontiers in cell and …, 2021 - frontiersin.org
Wnt proteins comprise a large family of highly conserved glycoproteins known for their role
in development, cell fate specification, tissue regeneration, and tissue homeostasis …
in development, cell fate specification, tissue regeneration, and tissue homeostasis …
The WNT signaling pathways in wound healing and fibrosis
O Burgy, M Königshoff - Matrix Biology, 2018 - Elsevier
The WNT signaling pathways are major regulators of organ development. Ample research
over the past few decades revealed that these pathways are critically involved in adult tissue …
over the past few decades revealed that these pathways are critically involved in adult tissue …
Wnt signaling mediates TLR pathway and promote unrestrained adipogenesis and metaflammation: therapeutic targets for obesity and type 2 diabetes
Diabesity is the combination of type 2 diabetes and obesity characterized by chronic low-
grade inflammation. The Wnt signaling act as an evolutionary pathway playing crucial role in …
grade inflammation. The Wnt signaling act as an evolutionary pathway playing crucial role in …
Targeting breast cancer stem cells through retinoids: a new hope for treatment
Breast cancer is a complex and diverse disease accounting for nearly 30% of all cancers
diagnosed in females. But unfortunately, patients develop resistance to the existing …
diagnosed in females. But unfortunately, patients develop resistance to the existing …
Cinnamon extract combined with high-intensity endurance training alleviates metabolic syndrome via non-canonical WNT signaling
Objectives The incidence of metabolic syndrome (MetS) in menopausal women is one of the
main health care concerns. MetS clusters are related to an imbalance in pro-and anti …
main health care concerns. MetS clusters are related to an imbalance in pro-and anti …