Background Cardiovascular disease (CVD) is the leading cause of death worldwide and
considered one of the most environmentally driven diseases. The role of DNA methylation in …

There is increasing interest in understanding the potential for epigenetic factors to contribute
to phenotypic diversity in evolutionary biology. One well studied epigenetic mechanism is …

Methylation of cytosines is a prototypic epigenetic modification of the DNA. It has been
implicated in various regulatory mechanisms across the animal kingdom and particularly in …

Identifying methylation quantitative trait loci (meQTLs) and integrating them with disease-
associated variants from genome-wide association studies (GWAS) may illuminate …

Aging, a universal process that affects all cells in an organism, is a major risk factor for a
group of neuropathies called glaucoma, where elevated intraocular pressure is one of the …

Preconception environmental conditions have been demonstrated to shape sperm
epigenetics and subsequently offspring health and development. Our previous findings in …

Although toxicology uses animal models to represent real-world human health scenarios, a
critical translational gap between laboratory-based studies and epidemiology remains. In …

Sperm is essential for successful artificial insemination in dairy cattle, and its quality can be
influenced by both epigenetic modification and epigenetic inheritance. The bovine germline …

Social epigenomics has emerged as an integrative field of research focused on identification
of socio-environmental factors, their influence on human biology through epigenomic …

Childhood trauma (CT) is well established as a potent risk factor for the development of
mental disorders. However, the potential of adverse early experiences to exert chronic and …