[HTML][HTML] Synergistic effects of inhaled aztreonam plus tobramycin on hypermutable cystic fibrosis Pseudomonas aeruginosa isolates in a dynamic biofilm model …

SKJ Breen, M Harper, C López-Causapé… - International journal of …, 2024 - Elsevier
Abstract Objective Hypermutable Pseudomonas aeruginosa strains are highly prevalent in
chronic lung infections of patients with cystic fibrosis (CF). Acute exacerbations of these …

De Novo Arginine Synthesis Is Required for Full Virulence of Xanthomonas arboricola pv. juglandis During Walnut Bacterial Blight Disease

CHD Sagawa, RAB Assis, PA Zaini, H Saxe… - …, 2022 - Am Phytopath Society
Walnut blight (WB) disease caused by Xanthomonas arboricola pv. juglandis (Xaj) threatens
orchards worldwide. Nitrogen metabolism in this bacterial pathogen is dependent on …

Antibiotic discovery with artificial intelligence for the treatment of Acinetobacter baumannii infections

Y Boulaamane, I Molina Panadero, A Hmadcha… - Msystems, 2024 - Am Soc Microbiol
Global challenges presented by multidrug-resistant Acinetobacter baumannii infections
have stimulated the development of new treatment strategies. We reported that outer …

[HTML][HTML] OprG harnesses the dynamics of its extracellular loops to transport small amino acids across the outer membrane of Pseudomonas aeruginosa

I Kucharska, P Seelheim, T Edrington, B Liang… - Structure, 2015 - cell.com
OprG is an outer membrane protein of Pseudomonas aeruginosa whose function as an
antibiotic-sensitive porin has been controversial and not well defined. Circumstantial …

[HTML][HTML] New insights on the reorganization of gene transcription in Pseudomonas putida KT2440 at elevated pressure

S Follonier, IF Escapa, PM Fonseca, B Henes… - Microbial cell …, 2013 - Springer
Background Elevated pressure, elevated oxygen tension (DOT) and elevated carbon
dioxide tension (DCT) are readily encountered at the bottom of large industrial bioreactors …

[HTML][HTML] Functional insights from proteome-wide structural modeling of Treponema pallidum subspecies pallidum, the causative agent of syphilis

S Houston, KV Lithgow, KK Osbak, CR Kenyon… - BMC Structural …, 2018 - Springer
Background Syphilis continues to be a major global health threat with 11 million new
infections each year, and a global burden of 36 million cases. The causative agent of …

[HTML][HTML] Roles of OmpA in Type III Secretion System-Mediated Virulence of Enterohemorrhagic Escherichia coli

H Hirakawa, K Suzue, A Takita, H Tomita - Pathogens, 2021 - mdpi.com
Outer membrane proteins are commonly produced by gram-negative bacteria, and they
have diverse functions. A subgroup of proteins, which includes OmpA, OmpW and OmpX, is …

Fosmidomycin transport through the phosphatespecific porins OprO and OprP of Pseudomonas aeruginosa

C Piselli, R Benz - Molecular microbiology, 2021 - Wiley Online Library
Abstract The Gramnegative bacterium Pseudomonas aeruginosa is an opportunistic
pathogen, responsible for many hospitalacquired infections. The bacterium is quite …

[HTML][HTML] Factor H-related protein 1 promotes complement-mediated opsonization of Pseudomonas aeruginosa

A Gonzalez-Alsina, H Martín-Merinero… - Frontiers in Cellular …, 2024 - frontiersin.org
Pseudomonas aeruginosa is an important human opportunistic pathogen responsible for a
wide range of infections. The complement system is the main early host defense mechanism …

[HTML][HTML] OmpW of Caulobacter crescentus Functions as an Outer Membrane Channel for Cations

R Benz, MD Jones, F Younas, E Maier, N Modi… - PLoS …, 2015 - journals.plos.org
Caulobacter crescentus is an oligotrophic bacterium that lives in dilute organic environments
such as soil and freshwater. This bacterium represents an interesting model for cellular …