[HTML][HTML] Nitrate and nitrite contamination in drinking water and cancer risk: A systematic review with meta-analysis

R Picetti, M Deeney, S Pastorino, MR Miller… - Environmental …, 2022 - Elsevier
Background Pollution of water sources, largely from wide-scale agricultural fertilizer use has
resulted in nitrate and nitrite contamination of drinking water. The effects on human health of …

[HTML][HTML] Drinking water nitrate and human health: an updated review

MH Ward, RR Jones, JD Brender, TM De Kok… - International journal of …, 2018 - mdpi.com
Nitrate levels in our water resources have increased in many areas of the world largely due
to applications of inorganic fertilizer and animal manure in agricultural areas. The regulatory …

Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate‐nitrite‐nitric oxide pathway

S Lidder, AJ Webb - British journal of clinical pharmacology, 2013 - Wiley Online Library
The discovery that dietary (inorganic) nitrate has important vascular effects came from the
relatively recent realization of the 'nitrate‐nitrite‐nitric oxide (NO) pathway'. Dietary nitrate …

A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this association

AJ Cross, LM Ferrucci, A Risch, BI Graubard, MH Ward… - Cancer research, 2010 - AACR
Although the relation between red and processed meat intake and colorectal cancer has
been reported in several epidemiologic studies, very few investigated the potential …

Nitrate and nitrite in the diet: how to assess their benefit and risk for human health

M Habermeyer, A Roth, S Guth, P Diel… - Molecular nutrition & …, 2015 - Wiley Online Library
Nitrate is a natural constituent of the human diet and an approved food additive. It can be
partially converted to nitrogen monoxide, which induces vasodilation and thereby decreases …

[HTML][HTML] Association between dietary nitrate, nitrite intake, and site-specific cancer risk: a systematic review and meta-analysis

K Said Abasse, EE Essien, M Abbas, X Yu, W Xie… - Nutrients, 2022 - mdpi.com
Background: People consume nitrates, nitrites, nitrosamines, and NOCs compounds
primarily through processed food. Many studies have yielded inconclusive results regarding …

Nitrate from drinking water and diet and bladder cancer among postmenopausal women in Iowa

RR Jones, PJ Weyer, CT DellaValle… - Environmental …, 2016 - ehp.niehs.nih.gov
Background: Nitrate is a drinking water contaminant arising from agricultural sources, and it
is a precursor in the endogenous formation of N-nitroso compounds (NOC), which are …

Too much of a good thing? Nitrate from nitrogen fertilizers and cancer

MH Ward - Reviews on environmental health, 2009 - degruyter.com
Man-made nitrogen fertilizers became widely used in US agriculture after WWII, providing an
inexpensive source of nitrogen and other plant nutrients that resulted in huge increases in …

Red and processed meat, nitrite, and heme iron intakes and postmenopausal breast cancer risk in the NIH‐AARP D iet and H ealth S tudy

M Inoue‐Choi, R Sinha, GL Gierach… - International journal of …, 2016 - Wiley Online Library
Previous studies have shown inconsistent associations between red and processed meat
intake and breast cancer risk. N‐nitroso compounds and heme iron have been hypothesized …

[HTML][HTML] Ingested nitrate, disinfection by-products, and risk of colon and rectal cancers in the Iowa Women's Health Study cohort

RR Jones, CT DellaValle, PJ Weyer, K Robien… - Environment …, 2019 - Elsevier
Background N-nitroso compounds (NOC) formed endogenously after nitrate/nitrite ingestion
and disinfection by-products (DBPs) are suspected colorectal carcinogens, but …