This paper comprises an updated version of the 2014 review which reported 1846 volatile
organic compounds (VOCs) identified from healthy humans. In total over 900 additional …

The article starts with a brief history of discovery of cancer biomarkers followed by statistical
data on published cancer biomarkers detection strategies in the last decade to demonstrate …

The unprecedented medical achievements of the last century have dramatically improved
our quality of life. Today, the high cost of many healthcare approaches challenges their long …

A new non-invasive and potentially inexpensive frontier in the diagnosis of cancer relies on
the detection of volatile organic compounds (VOCs) in exhaled breath samples. Breath can …

Background Despite the efficacy of immune checkpoint inhibitors (ICIs) only the 20–30% of
treated patients present long term benefits. The metabolic changes occurring in the gut …

The detection of many diseases is missed because of delayed diagnoses or the low efficacy
of some treatments. This emphasizes the urgent need for inexpensive and minimally …

Cancer is the second leading cause of death in the world. Because tumors detected at early
stages are easier to treat, the search for biomarkers—especially non-invasive ones—that …

Various diseases increasingly challenge the health status and life quality of human beings.
Volatolome emitted from patients has been considered as a potential family of markers …

Volatile organic compounds (VOCs) have shown potential as non-invasive breath
biomarkers for lung cancer, but their unclear biological origin currently limits clinical …

Currently, in clinical practice there is a pressing need for potential biomarkers that can
identify lung cancer at early stage before becoming symptomatic or detectable by …