Software tools, databases and resources in metabolomics: updates from 2018 to 2019
Metabolomics has evolved as a discipline from a discovery and functional genomics tool,
and is now a cornerstone in the era of big data-driven precision medicine. Sample …
and is now a cornerstone in the era of big data-driven precision medicine. Sample …
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral proteins bind to host
mitochondrial proteins, likely inhibiting oxidative phosphorylation (OXPHOS) and stimulating …
mitochondrial proteins, likely inhibiting oxidative phosphorylation (OXPHOS) and stimulating …
[PDF][PDF] Role of miR-2392 in driving SARS-CoV-2 infection
MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene
regulation that have a major impact on many diseases and provide an exciting avenue …
regulation that have a major impact on many diseases and provide an exciting avenue …
[HTML][HTML] Metabolomics for evaluating flavor-associated metabolites in plant-based products
S Pavagadhi, S Swarup - Metabolites, 2020 - mdpi.com
Plant-based diets (PBDs) are associated with environmental benefits, human health
promotion and animal welfare. There is a worldwide shift towards PBDs, evident from the …
promotion and animal welfare. There is a worldwide shift towards PBDs, evident from the …
[HTML][HTML] Targeted down regulation of core mitochondrial genes during SARS-CoV-2 infection
Defects in mitochondrial oxidative phosphorylation (OXPHOS) have been reported in COVID-
19 patients, but the timing and organs affected vary among reports. Here, we reveal the …
19 patients, but the timing and organs affected vary among reports. Here, we reveal the …
[PDF][PDF] System-wide transcriptome damage and tissue identity loss in COVID-19 patients
The molecular mechanisms underlying the clinical manifestations of coronavirus disease
2019 (COVID-19), and what distinguishes them from common seasonal influenza virus and …
2019 (COVID-19), and what distinguishes them from common seasonal influenza virus and …
[HTML][HTML] African Americans and European Americans exhibit distinct gene expression patterns across tissues and tumors associated with immunologic functions and …
The COVID-19 pandemic has affected African American populations disproportionately with
respect to prevalence, and mortality. Expression profiles represent snapshots of combined …
respect to prevalence, and mortality. Expression profiles represent snapshots of combined …
pyrpipe: a Python package for RNA-Seq workflows
The availability of terabytes of RNA-Seq data and continuous emergence of new analysis
tools, enable unprecedented biological insight. There is a pressing requirement for a …
tools, enable unprecedented biological insight. There is a pressing requirement for a …
Tissue-type specific accumulation of the plastoglobular proteome, transcriptional networks, and plastoglobular functions
EJS Michel, L Ponnala… - Journal of Experimental …, 2021 - academic.oup.com
Plastoglobules are dynamic protein–lipid microcompartments in plastids enriched for
isoprenoid-derived metabolites. Chloroplast plastoglobules support formation, remodeling …
isoprenoid-derived metabolites. Chloroplast plastoglobules support formation, remodeling …
[HTML][HTML] Landscape of the dark transcriptome revealed through re-mining massive RNA-Seq data
The “dark transcriptome” can be considered the multitude of sequences that are transcribed
but not annotated as genes. We evaluated expression of 6,692 annotated genes and 29,354 …
but not annotated as genes. We evaluated expression of 6,692 annotated genes and 29,354 …