The neurotoxin DSP-4 dysregulates the locus coeruleus-norepinephrine system and recapitulates molecular and behavioral aspects of prodromal neurodegenerative …
The noradrenergic locus coeruleus (LC) is among the earliest sites of tau and α-synuclein
pathology in Alzheimer's disease (AD) and Parkinson's disease (PD), respectively. The …
pathology in Alzheimer's disease (AD) and Parkinson's disease (PD), respectively. The …
Lithium engages autophagy for neuroprotection and neuroplasticity: Translational evidence for therapy
S Puglisi-Allegra, G Lazzeri, CL Busceti… - Neuroscience & …, 2023 - Elsevier
Here an overview is provided on therapeutic/neuroprotective effects of Lithium (Li+) in
neurodegenerative and psychiatric disorders focusing on the conspicuous action of Li+ …
neurodegenerative and psychiatric disorders focusing on the conspicuous action of Li+ …
Pathophysiological studies of monoaminergic neurotransmission systems in valproic acid-induced model of autism spectrum disorder
HY Kuo, FC Liu - Biomedicines, 2022 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex etiology.
The core syndromes of ASD are deficits in social communication and self-restricted interests …
The core syndromes of ASD are deficits in social communication and self-restricted interests …
Riddles in the dark: Decoding the relationship between neuromelanin and neurodegeneration in locus coeruleus neurons
AF Iannitelli, D Weinshenker - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
The noradrenergic locus coeruleus (LC) is among the first regions of the brain affected by
pathology in both Alzheimer's disease (AD) and Parkinson's disease (PD), but the reasons …
pathology in both Alzheimer's disease (AD) and Parkinson's disease (PD), but the reasons …
[HTML][HTML] Peripheral nerve stimulation: A neuromodulation-based approach
Recent technological improvements have positioned us at the threshold of innovative
discoveries that will assist in new perspectives and avenues of research. Increased attention …
discoveries that will assist in new perspectives and avenues of research. Increased attention …
[HTML][HTML] Circuit mechanisms of itch in the brain
D Mu, YG Sun - Journal of Investigative Dermatology, 2022 - Elsevier
Itch is an unpleasant somatic sensation with the desire to scratch, and it consists of sensory,
affective, and motivational components. Acute itch serves as a critical protective mechanism …
affective, and motivational components. Acute itch serves as a critical protective mechanism …
Locus Coeruleus magnetic resonance imaging: a comparison between native-space and template-space approach
Locus Coeruleus (LC) is the main noradrenergic nucleus of the brain, which is involved in
many physiological functions including cognition; its impairment may be crucial in the …
many physiological functions including cognition; its impairment may be crucial in the …
Serotonergic and noradrenergic contributions to motor cortical and spinal motoneuronal excitability in humans
JR Thorstensen, TT Henderson, JJ Kavanagh - Neuropharmacology, 2023 - Elsevier
Animal models indicate that motor behaviour is shaped by monoamine neuromodulators
released diffusely throughout the brain and spinal cord. As an alternative to conducting a …
released diffusely throughout the brain and spinal cord. As an alternative to conducting a …
Pupillary correlates of preparatory control in the Stroop task
N Unsworth, AL Miller - Attention, Perception, & Psychophysics, 2023 - Springer
In three experiments, individual differences in preparatory control in the Stroop task were
examined. Participants performed variants of the Stroop task while pupillary responses were …
examined. Participants performed variants of the Stroop task while pupillary responses were …
Age-dependent dysregulation of locus coeruleus firing in a transgenic rat model of Alzheimer's disease
MA Kelberman, JM Rorabaugh, CR Anderson… - Neurobiology of …, 2023 - Elsevier
Hyperphosphorylated tau in the locus coeruleus (LC) is ubiquitous in prodromal Alzheimer's
disease (AD), and LC neurons degenerate as AD progresses. Hyperphosphorylated tau …
disease (AD), and LC neurons degenerate as AD progresses. Hyperphosphorylated tau …