Neuroketotherapeutics: a modern review of a century-old therapy

SJ Koppel, RH Swerdlow - Neurochemistry international, 2018 - Elsevier
Neuroketotherapeutics represent a class of bioenergetic medicine therapies that feature the
induction of ketosis. These therapies include medium-chain triglyceride supplements …

Progesterone neuroprotection: the background of clinical trial failure

M Schumacher, C Denier, JP Oudinet, D Adams… - The Journal of steroid …, 2016 - Elsevier
Since the first pioneering studies in the 1990s, a large number of experimental animal
studies have demonstrated the neuroprotective efficacy of progesterone for brain disorders …

[HTML][HTML] Sleep, sleep disorders, and mild traumatic brain injury. What we know and what we need to know: findings from a national working group

EM Wickwire, SG Williams, T Roth, VF Capaldi, M Jaffe… - …, 2016 - Elsevier
Disturbed sleep is one of the most common complaints following traumatic brain injury (TBI)
and worsens morbidity and long-term sequelae. Further, sleep and TBI share …

Diagnosis of traumatic brain injury using miRNA signatures in nanomagnetically isolated brain-derived extracellular vesicles

J Ko, M Hemphill, Z Yang, E Sewell, YJ Na… - Lab on a Chip, 2018 - pubs.rsc.org
The accurate diagnosis and clinical management of traumatic brain injury (TBI) is currently
limited by the lack of accessible molecular biomarkers that reflect the pathophysiology of this …

Clinical applications of extracellular vesicles in the diagnosis and treatment of traumatic brain injury

K Beard, DF Meaney, D Issadore - Journal of neurotrauma, 2020 - liebertpub.com
Extracellular vesicles (EVs) have emerged as key mediators of cell-cell communication
during homeostasis and in pathology. Central nervous system (CNS)-derived EVs contain …

Microstructural and microglial changes after repetitive mild traumatic brain injury in mice

S Robinson, JB Berglass, JL Denson… - Journal of …, 2017 - Wiley Online Library
Traumatic brain injury (TBI) is a major public health issue, with recently increased
awareness of the potential long‐term sequelae of repetitive injury. Although TBI is common …

Translational neuroimaging in mild traumatic brain injury

TLT Wiegand, N Sollmann, EM Bonke… - Journal of …, 2022 - Wiley Online Library
Traumatic brain injuries (TBIs) are common with an estimated 27.1 million cases per year.
Approximately 80% of TBIs are categorized as mild TBI (mTBI) based on initial symptom …

The biological basis of chronic traumatic encephalopathy following blast injury: a literature review

M Aldag, RC Armstrong, F Bandak… - Journal of …, 2017 - liebertpub.com
Abstract The United States Department of Defense Blast Injury Research Program
Coordinating Office organized the 2015 International State-of-the-Science meeting to …

Late blood levels of neurofilament light correlate with outcome in patients with traumatic brain injury

J Tuure, M Mohammadian, O Tenovuo… - Journal of …, 2024 - liebertpub.com
Neurofilament light (NF-L) is an axonal protein that has shown promise as a traumatic brain
injury (TBI) biomarker. Serum NF-L shows a rather slow rise after injury, peaking after 1-2 …

Paradigm shift required for translational research on the brain

JH Yoon, D Lee, C Lee, E Cho, S Lee… - … & Molecular Medicine, 2024 - nature.com
Biomedical research on the brain has led to many discoveries and developments, such as
understanding human consciousness and the mind and overcoming brain diseases …