Visceral pain

L Grundy, A Erickson, SM Brierley - Annual review of physiology, 2019 - annualreviews.org
Most of us live blissfully unaware of the orchestrated function that our internal organs
conduct. When this peace is interrupted, it is often by routine sensations of hunger and urge …

Current and emerging pharmacological targets and treatments of urinary incontinence and related disorders

MC Michel, L Cardozo, CJ Chermansky, F Cruz… - Pharmacological …, 2023 - ASPET
Overactive bladder syndrome with and without urinary incontinence and related conditions,
signs, and disorders such as detrusor overactivity, neurogenic lower urinary tract …

Cooperative assembly of a designer peptide and silk fibroin into hybrid nanofiber gels for neural regeneration after spinal cord injury

F Feng, X Song, Z Tan, Y Tu, L Xiao, P Xie, Y Ma… - Science …, 2023 - science.org
Local reconstruction of a permissive environment with biomaterials is a promising strategy to
treat spinal cord injury (SCI). We reported a hybrid hydrogel fabricated from a small …

Mechanisms underlying overactive bladder and interstitial cystitis/painful bladder syndrome

L Grundy, A Caldwell, SM Brierley - Frontiers in neuroscience, 2018 - frontiersin.org
The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal
cord, providing sensory input to the micturition centers within the central nervous system …

Central pattern generators in the brainstem and spinal cord: an overview of basic principles, similarities and differences

I Steuer, PA Guertin - Reviews in the Neurosciences, 2019 - degruyter.com
Central pattern generators (CPGs) are generally defined as networks of neurons capable of
enabling the production of central commands, specifically controlling stereotyped, rhythmic …

Lumbosacral spinal cord epidural stimulation improves voiding function after human spinal cord injury

AN Herrity, CS Williams, CA Angeli, SJ Harkema… - Scientific reports, 2018 - nature.com
Deficits in urologic function after spinal cord injury (SCI) manifest both as a failure to store
and empty, greatly impacting daily life. While current management strategies are necessary …

Effectiveness of percutaneous tibial nerve stimulation in the treatment of overactive bladder syndrome

LL de Wall, JPFA Heesakkers - Research and reports in urology, 2017 - Taylor & Francis
Overactive bladder syndrome (OAB) is a common condition affecting adults and children
worldwide, resulting in a substantial economic and psychological burden. Percutaneous …

Applications of polymers for organ-on-chip technology in urology

B Galateanu, A Hudita, EI Biru, H Iovu, C Zaharia… - Polymers, 2022 - mdpi.com
Organ-on-chips (OOCs) are microfluidic devices used for creating physiological organ
biomimetic systems. OOC technology brings numerous advantages in the current landscape …

[HTML][HTML] Histamine induces peripheral and central hypersensitivity to bladder distension via the histamine H1 receptor and TRPV1

L Grundy, A Caldwell, SG Caraballo… - American Journal …, 2020 - journals.physiology.org
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a common chronic pelvic disorder with
sensory symptoms of urinary urgency, frequency, and pain, indicating a key role for …

Implantable Multi-Cross-Linked Membrane-Ionogel Assembly for Reversible Non-Faradaic Neurostimulation

JS Kim, J Kim, JW Lim, DJ Kim, JI Lee, H Choi… - ACS …, 2023 - ACS Publications
Neural interfaces play a major role in modulating neural signals for therapeutic purposes. To
meet the demand of conformable neural interfaces for developing bioelectronic medicine …