The extended granin family: structure, function, and biomedical implications

A Bartolomucci, R Possenti, SK Mahata… - Endocrine …, 2011 - academic.oup.com
The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …

Catecholamines, cardiac natriuretic peptides and chromogranin A: evolution and physiopathology of a 'whip-brake'system of the endocrine heart

B Tota, MC Cerra, A Gattuso - Journal of Experimental …, 2010 - journals.biologists.com
In the past 50 years, extensive evidence has shown the ability of vertebrate cardiac non-
neuronal cells to synthesize and release catecholamines (CA). This formed the mindset …

Malvidin, a red wine polyphenol, modulates mammalian myocardial and coronary performance and protects the heart against ischemia/reperfusion injury

AM Quintieri, N Baldino, E Filice, L Seta, A Vitetti… - The Journal of nutritional …, 2013 - Elsevier
A moderate red wine consumption and a colored fruit-rich diet protect the cardiovascular
system, thanks to the presence of several polyphenols. Malvidin-3-0-glucoside (malvidin) …

Full-length human chromogranin-A cardioactivity: myocardial, coronary, and stimulus-induced processing evidence in normotensive and hypertensive male rat hearts

T Pasqua, A Corti, S Gentile, L Pochini, M Bianco… - …, 2013 - academic.oup.com
Plasma chromogranin-A (CgA) concentrations correlate with severe cardiovascular
diseases, whereas CgA-derived vasostatin-I and catestatin elicit cardiosuppression via an …

Granins and granin-related peptides in neuroendocrine tumours

GM Portela-Gomes, L Grimelius, E Wilander… - Regulatory peptides, 2010 - Elsevier
This review focus on neuroendocrine tumours (NETs), with special reference to the
immunohistochemical analysis of granins and granin-related peptides and their usefulness …

Antiarrhythmic effects of vasostatin‐1 in a canine model of atrial fibrillation

S Stavrakis, BJ Scherlag, Y Fan, Y Liu… - Journal of …, 2012 - Wiley Online Library
Antiarrhythmic Effects of Vasostatin‐1. Background: We examined the antiarrhythmic effects
of vasostatin‐1, a recently identified cardioregulatory peptide, in canine models of atrial …

The interplay between chromogranin A-derived peptides and cardiac natriuretic peptides in cardioprotection against catecholamine-evoked stress

R Mazza, S Imbrogno, B Tota - Regulatory peptides, 2010 - Elsevier
Chromogranin A (CgA) is the major soluble protein co-stored and co-released with
catecholamines (CAs) from secretory vesicles in the adrenal medulla chromaffin cells …

[HTML][HTML] Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production

M Kakoki, EM Bahnson, JR Hagaman, RM Siletzky… - JCI insight, 2019 - ncbi.nlm.nih.gov
Engulfment and cell motility protein 1 (ELMO1) is part of a guanine nucleotide exchange
factor for Ras-related C3 botulinum toxin substrate (Rac), and ELMO1 polymorphisms were …

Chromogranin A (CGA)-derived polypeptide (CGA47–66) inhibits TNF-α-induced vascular endothelial hyper-permeability through SOC-related Ca2+ signaling

L Luo, SY Liu, D Zhang, F Wei, NN Gu, Y Zeng… - Peptides, 2020 - Elsevier
Abstract CGA 1− 78 (Vasostatin-1, VS-1) a N-terminal Chromogranin A (CGA)-derived
peptide, has been shown to have a protective effect against TNF-α-induced impairment of …

Endothelium dependent cardiovascular effects of the chromogranin A-derived peptides vasostatin-1 and catestatin

S Fornero, E Bassino, MP Gallo… - Current medicinal …, 2012 - ingentaconnect.com
The involvement of Chromogranin A (CgA) in the cardiovascular function regulation is
attributed to its function as a prohormone. Several studies indicated that CgA-derived …