Overt hypothyroidism in pregnancy, defined as an elevated serum thyroid-stimulating
hormone (TSH) and reduced serum free thyroxine or a TSH> 10 mIU/L, is known to have …

This review investigated which patterns of thyroid-and brain-related effects are seen in rats
upon gestational/lactational exposure to 14 substances causing thyroid hormone imbalance …

Context Overt thyroid disease in pregnancy is a known risk factor for abnormal fetal growth
and development. Data on the effects of milder forms of variation in maternal thyroid function …

Background Contemporary human populations are exposed to elevated concentrations of
organophosphate esters (OPEs) and phthalates. Some metabolites have been linked with …

Background Iodine deficiency early in the life cycle—the “first 1000 days”—can cause
hypothyroidism and irreversibly impair neuromotor development. However, the relative …

Gestational hypothyroidism can impair development, cognition, and mood. Here, we tested
whether multisensory stimulation (MS) improves the phenotype of rats born to surgically …

Background Preeclampsia is a leading cause of maternal mortality and morbidity in South
Africa. Iodine deficiency in pregnancy, which is amenable to correction through iodine …

Background Maternal thyroid function plays an important role in foetal brain development;
however, little consensus exists regarding the relationship between normal variability in …

Background Evidence has indicated that polyunsaturated fatty acids (PUFAs)-enriched diet
could reduce inflammation due to thyroid autoimmunity in vivo, and therefore, enhance …

Abstract Background The American Thyroid Association (ATA) recommended the
establishment of population specific reference ranges for thyroid hormones during …