Zika virus (ZIKV) is an emerging virus from the Flaviviridae family that is transmitted to
humans by mosquito vectors and represents an important health problem. Infections in …

In recent decades, mosquito-borne illnesses have emerged as a major health burden in
many tropical regions. These diseases, such as malaria, dengue fever, chikungunya, yellow …

Maternal infections are among the main risk factors for cognitive impairments in the
offspring. Zika virus (ZIKV) can be transmitted vertically, causing a set of heterogeneous birth …

Background MicroRNAs (miRNAs) play critical roles in regulating virus infection and
replication. However, the mechanism by which miRNA regulates Zika virus (ZIKV) replication …

During pregnancy, a series of physiological changes are determined at the molecular,
cellular and macroscopic level that make the mother and fetus more susceptible to certain …

Lipids play essential roles in the cell as components of cellular membranes, signaling
molecules, and energy storage sources. Lipid droplets are cellular organelles composed of …

In order to prevent new pathogen outbreaks and avoid possible new global health threats, it
is important to study the mechanisms of microbial pathogenesis, screen new antiviral agents …

Abstract In February 2016, the World Health Organization declared Zika virus (ZIKV)
infection a public health emergency of international concern because it caused congenital …

This study aims to evaluate the antiviral potential of the nucleoside analogue favipiravir
(FAV) against ZIKV, an arbovirus for which there are no approved antiviral therapies, in three …

Autophagy is a lysosomal degradative pathway, which regulates the homeostasis of
eukaryotic cells. This pathway can degrade misfolded or aggregated proteins, clear …