Digital health technologies (DHTs) present unique opportunities for clinical evidence
generation but pose certain challenges. These challenges stem, in part, from existing …

Recently, companies such as Apple Inc, Fitbit Inc, and Garmin Ltd have released new
wearable blood oxygenation measurement technologies. Although the release of these …

The objective was to exploit the raw data output from a scalable home cage (type IIL IVC)
monitoring (HCM) system (DVC®), to characterize pattern of undisrupted rest and physical …

Background At present, the function of isothermal microcalorimetry (IMC) calscreener in
detecting alterations in the metabolic pathways of cancer cells remains unexplored. We …

The purpose of this study was to determine potential metabolic biomarkers and therapeutic
drugs in the gingival tissue of individuals with periodontitis. Liquid chromatography–mass …

The α-hydroxy acid oxidoreductase (HAOx) family contains a diverse group of enzymes that
can be applied in biosensors for L-lactate detection, most prominently lactate oxidase (LOx) …

Instrumented balance and gait test are an important component of physical capability
assessment in clinical examinations. This study provides insight to a new generation Open …

This study aims to establish a scientific foundation for early detection and diagnosis of
silicosis by conducting meta-analysis on the role of single biomarkers in independent …

Recently, digital health technologies (DHTs) and digital biomarkers have gained a lot of
traction in clinical investigations, motivating sponsors, investigators, and regulators to …

The increasing use of inertial measurement units (IMU) in biomedical sciences brings new
possibilities for clinical research. The aim of this paper is to demonstrate the accuracy of the …