Malaria prevention in children: an update

DAJ Friedman-Klabanoff, D Adu-Gyasi… - Current Opinion in …, 2024 - journals.lww.com
While challenges remain in malaria control towards elimination, new guidelines and recently
approved vaccines offer hope. Monitoring for continued vaccine and chemoprevention …

[HTML][HTML] How to Accelerate Early Stage of Malaria Vaccine Development by Optimizing Functional Assays

K Miura - Vaccines, 2024 - mdpi.com
While two Plasmodium falciparum circumsporozoite protein-based pre-erythrocytic vaccines
(PEV), RTS, S and R21, have been approved by the WHO, no blood-stage vaccine (BSV) or …

[HTML][HTML] Clinical formulation development of Plasmodium falciparum malaria vaccine candidates based on Pfs48/45, Pfs230, and PfCSP

J Plieskatt, P Bang, GK Wood, M Naghizadeh… - Vaccine, 2024 - Elsevier
Two malaria transmission-blocking vaccine (TBV) candidates, R0. 6C and ProC6C, have
completed preclinical development including the selection of adjuvants, Alhydrogel® with or …

[HTML][HTML] Atypical memory B cell frequency correlates with antibody breadth and function in malaria immune adults

FD Partey, JNN Dowuona, ANA Pobee, MR Walker… - Scientific Reports, 2024 - nature.com
Clinical immunity to malaria develops slowly after repeated episodes of infection and
antibodies are essential in naturally acquired immunity against malaria. However, chronic …

[HTML][HTML] Biochemical characteristics of patients with imported malaria

D Bi, J Lin, X Luo, L Lin, X Tang, X Luo, Y Lu… - Frontiers in cellular …, 2022 - frontiersin.org
Objectives This study aimed to investigate the clinical and biochemical profiles of patients
with imported malaria infection between 1 January 2011 and 30 April 2022 and admitted to …

[HTML][HTML] Genetic diversity of glutamate-rich protein (GLURP) in Plasmodium falciparum isolates from school-age children in Kinshasa, DRC

KMM Paul, SV Simpson, SS Nundu, H Arima… - Parasitology …, 2024 - Elsevier
Malaria infections in school-age children further make it difficult to control the disease's
spread. Moreover, the genetic diversity of glutamate-rich protein, potentially a candidate for …

[HTML][HTML] Malaria vaccine approaches leveraging technologies optimized in the COVID-19 era

BN Kanoi, M Maina, C Likhovole, FM Kobia… - Frontiers in Tropical …, 2022 - frontiersin.org
Africa bears the greatest burden of malaria with more than 200 million clinical cases and
more than 600,000 deaths in 2020 alone. While malaria-associated deaths dropped steadily …

Development and validation of serological assays to evaluate malaria transmission

TE Oulton - 2023 - researchonline.lshtm.ac.uk
In 2007, the aim to eradicate malaria was revived and reinvigorated, taking into account the
experiences and lessons of the earlier efforts initiated in the mid 1950's. In particular, it was …