The lysosomal degradation of several sphingolipids requires the presence of four small
glycoproteins called saposins, generated by proteolytic processing of a common precursor …

Although catalyzed by different proteins, the energy barriers for lipid bilayer fusion in
exocytosis, viral fusion, and trafficking seem to be the same as those for the fusion of protein …

Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

Fatty acid derivatives are abundant in biological membranes, mainly as components of
phospholipids and cholesterol esters. Their presence, free or bound to phospholipids …

A new theory for the molecular mechanism of sludge granulation, namely proton
translocation-dehydration theory, was proposed in this study. Based on the consideration of …

Semliki Forest virus (SFV) utilizes a membrane fusion strategy to introduce its genome into
the host cell. After binding to cell-surface receptors, virus particles are internalized through …

Low-pH-induced membrane fusion of Semliki Forest virus (SFV) in a model system is
mediated by sphingolipids in the target membrane; ceramide is the sphingolipid minimally …

Publisher Summary This chapter has its focus on applications of phospholipid vesicles for
the elucidation of molecular mechanisms of membrane fusion. Rather than presenting a …

Liposomes have been proposed as a means to target intra-articularly injected anti-
inflammatory agents to phagocytic cells in inflamed synovial joints. Clodronate …

As a novel fusogenic liposome, we designed liposomes modified with poly (glycidol) having
β-alanine residues, which is a poly (ethylene glycol) derivative with positively charged …