BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of
anovulatory infertility. An endometrial component has been suggested to contribute to …

BACKGROUND Early reproductive failure is the most common complication of pregnancy
with only 30% of conceptions reaching live birth. Establishing a successful pregnancy …

The initiation of human pregnancy is marked by the implantation of an embryo into the
uterine environment; however, the underlying mechanisms remain largely elusive. To …

Cryopreservation of human embryos is now a routine procedure in assisted reproductive
technologies laboratories. There is no consensus on the superiority of any protocol, and …

Prior studies have provided conflicting results regarding the use of platelet-rich plasma
(PRP) in women undergoing in-vitro fertilization (IVF) or intracytoplasmic injection (ICSI) …

Introduction: Despite great advances in assisted reproductive technology (ART), recurrent
implantation failure (RIF) cannot be effectively avoided. Notably, cellular characteristics and …

Decidualization renders the endometrium transiently receptive to an implanting blastocyst
although the underlying mechanisms remain incompletely understood. Here we show that …

Despite expanding global experience with advanced reproductive technologies, the majority
of IVF attempts do not result in a successful pregnancy, foremost as a result of implantation …

Recurrent implantation failure (RIF) is a multifactorial condition affecting 10–15% of in vitro
fertilization (IVF) couples. Data suggest that functional dysregulation of the endometrial …

STUDY QUESTION Can we reconstitute physiologically relevant 3-dimensional (3D)
microengineered endometrium in-vitro model? SUMMARY ANSWER Our representative …