Leprosy is caused by Mycobacterium leprae (M. leprae) and M. lepromatosis, an obligate
intracellular organism, and over 200,000 new cases occur every year. M. leprae parasitizes …

Mycobacterial pathogens can be categorized into three broad groups: Mycobacterium
tuberculosis complex causing tuberculosis, M. leprae and M. lepromatosis causing leprosy …

Background Leprosy diagnosis is mainly based on clinical evaluation, although this
approach is difficult, especially for untrained physicians. We conducted a temporary …

Background Leprosy is caused by Mycobacterium leprae and Mycobacterium lepromatosis.
Most of the affected population lives in low-income countries and may take up to 10 years to …

B-cells, in addition to antibody secretion, have emerged increasingly as effector and
immunoregulatory cells in several chronic inflammatory diseases. Although Erythema …

Leprosy remains endemic in several developing countries, such as India and Brazil, in part
due to delayed diagnosis that facilitates ongoing transmission. Although immunoglobulins …

BACKGROUND Leprosy remains a health problem in many countries, with difficulties in
diagnosis resulting in delayed treatment and more severe disabilities. Antibodies against …

Abstract Background Mycobacterium leprae and Mycobacterium lepromatosis are gram-
positive bacterial pathogens and the causative agents of leprosy in humans across the …

This study investigates the efficacy of proteomic analysis of human remains to identify active
infections in the past through the detection of pathogens and the host response to infection …

Background Immunological biomarkers have often been used as a complementary
approach to support clinical diagnosis in several infectious diseases. The lack of …