Research progress on the synthesis and pharmacology of 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole derivatives: a mini review
JJ Wang, W Sun, WD Jia, M Bian… - Journal of Enzyme …, 2022 - Taylor & Francis
Oxadiazole is a five-membered heterocyclic compound containing two nitrogen atoms and
one oxygen atom. The 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole have favourable physical …
one oxygen atom. The 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole have favourable physical …
Synthesis, biological evaluation, and molecular docking studies of novel diclofenac derivatives as antibacterial agents
In the recent years, interest in the synthesis of diclofenac derivatives has increased due to
their exceptional biological activity. We present here the synthesis of some novel diclofenac …
their exceptional biological activity. We present here the synthesis of some novel diclofenac …
Design, synthesis and antibacterial activity of novel pleuromutilin derivatives with thieno [2, 3-d] pyrimidine substitution
R Ding, X Wang, J Fu, Y Chang, Y Li, Y Liu… - European Journal of …, 2022 - Elsevier
A series of novel pleuromutilin derivatives with substituted thienopyrimidines were designed,
synthesized, and evaluated for antibacterial act ivity. In this study, the activities of these …
synthesized, and evaluated for antibacterial act ivity. In this study, the activities of these …
Solid-state luminescent materials containing both indole and pyrimidine moieties: Design, synthesis, and density functional theory calculations
Heterocyclic compounds with effective solid-state luminescence offer a wide range of uses. It
has been observed that combining pyrimidine and indole moieties in a single molecule can …
has been observed that combining pyrimidine and indole moieties in a single molecule can …
Synthesis and intriguing single-component white-light emission from oxadiazole or thiadiazole integrated with coumarin luminescent core
There has been evidence of non-typical fluorescence activities in thiadiazole and
oxadiazole derivatives. Also, some coumarin compounds with tunable luminescence …
oxadiazole derivatives. Also, some coumarin compounds with tunable luminescence …
From blue to green photoluminescence: Design, synthesis, and DFT calculations of heterocyclic compounds containing chromenothienopyrimidine moiety
MS Tolba, AF Al‐Hossainy… - Asian Journal of …, 2022 - Wiley Online Library
Incorporating coumarin nuclei into other heterocyclic scaffolds such as thienopyrimidine can
significantly increase the photophysical and biological efficiency. Accordingly, we describe …
significantly increase the photophysical and biological efficiency. Accordingly, we describe …
[HTML][HTML] Green synthesis of some tetrahydroquinoline derivatives and evaluation as anticancer agents
NMM Alanazi, IO Althobaiti, YA El-Ossaily… - Arabian Journal of …, 2023 - Elsevier
This study demonstrates the design and synthesis of heterocyclic compounds with diverse
biological effects. Using an ionic liquid catalyst, a sonosynthetic approach for the assembly …
biological effects. Using an ionic liquid catalyst, a sonosynthetic approach for the assembly …
Fused Thienopyrimidines as Versatile Pharmacophores for the Development of Cyclooxygenase‐2 Inhibitors
Inflammation is an essential body immune system response against various infections and
tissue injuries and maintains normal homeostasis. Alterations in inflammatory responses …
tissue injuries and maintains normal homeostasis. Alterations in inflammatory responses …
Synthesis, computational drug likeness, DFT studies and in vitro biological activity evaluation of some heteronuclear complexes of functionalized (E)‐2‐(butan‐2 …
The dinuclear complexes of Schiff bases possess interesting structures and activity
spectrum. Five mixed metal complexes of 2‐butanone thiosemicarbazone were prepared …
spectrum. Five mixed metal complexes of 2‐butanone thiosemicarbazone were prepared …
Antimicrobial Evaluation of Sulfonamides after Coupling with Thienopyrimidine Coplanar Structure
EI Elmongy, WS Alanazi, AI Aldawsari, AA Alfaouri… - Pharmaceuticals, 2024 - mdpi.com
This work describes the design and synthesis of three series of hybrids of thienopyrimidines
and sulfonamides. Dihydrofolate reductase enzyme was selected as a target for the in-silico …
and sulfonamides. Dihydrofolate reductase enzyme was selected as a target for the in-silico …