Emergence of SARS-CoV-2 Omicron (B. 1.1. 529) variant, salient features, high global health concerns and strategies to counter it amid ongoing COVID-19 pandemic

R Khandia, S Singhal, T Alqahtani, MA Kamal… - Environmental …, 2022 - Elsevier
Since the appearance in the late of December 2019, SARS-CoV-2 is rapidly evolving and
mutating continuously, giving rise to various variants with variable degrees of infectivity and …

A detailed overview of immune escape, antibody escape, partial vaccine escape of SARS-CoV-2 and their emerging variants with escape mutations

C Chakraborty, AR Sharma, M Bhattacharya… - Frontiers in …, 2022 - frontiersin.org
The infective SARS-CoV-2 is more prone to immune escape. Presently, the significant
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …

A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection

DA Jamison Jr, S Anand Narayanan… - European Journal of …, 2022 - nature.com
COVID-19, the disease caused by SARS-CoV-2, has claimed approximately 5 million lives
and 257 million cases reported globally. This virus and disease have significantly affected …

Epistatic models predict mutable sites in SARS-CoV-2 proteins and epitopes

J Rodriguez-Rivas, G Croce… - Proceedings of the …, 2022 - National Acad Sciences
The emergence of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) is a major concern given their potential impact on the transmissibility and …

[HTML][HTML] Mutations of SARS-CoV-2 spike protein: Implications on immune evasion and vaccine-induced immunity

HM Mengist, AJK Kombe, D Mekonnen, A Abebaw… - Seminars in …, 2021 - Elsevier
Responsible for more than 4.9 million deaths so far, COVID-19, caused by SARS-CoV-2, is
instigating devastating effects on the global health care system whose impacts could be …

[HTML][HTML] Omicron variant: Current insights and future directions

R Rana, R Kant, RS Huirem, D Bohra… - Microbiological …, 2022 - Elsevier
The global COVID-19 outbreak has returned with the identification of the SARS-CoV-2
Omicron variant (B. 1.1. 529) after appearing to be persistently spreading for the more than …

Evolution of SARS-CoV-2 variants: implications on immune escape, vaccination, therapeutic and diagnostic strategies

NZ Zabidi, HL Liew, IA Farouk, A Puniyamurti, AJW Yip… - Viruses, 2023 - mdpi.com
The COVID-19 pandemic caused by SARS-CoV-2 is associated with a lower fatality rate
than its SARS and MERS counterparts. However, the rapid evolution of SARS-CoV-2 has …

Spike Protein NTD mutation G142D in SARS-CoV-2 Delta VOC lineages is associated with frequent back mutations, increased viral loads, and immune evasion

L Shen, TJ Triche, JD Bard, JA Biegel, AR Judkins… - MedRxiv, 2021 - medrxiv.org
The significantly greater infectivity of the SARS-CoV-2 Delta variants of concern (VOC) is
hypothesized to be driven by key mutations that result in increased transmissibility, viral load …

Severity, pathogenicity and transmissibility of delta and lambda variants of SARS-CoV-2, toxicity of spike protein and possibilities for future prevention of COVID-19

M Moghaddar, R Radman, I Macreadie - Microorganisms, 2021 - mdpi.com
The World Health Organization reports that SARS-CoV-2 has infected over 220 million
people and claimed over 4.7 million lives globally. While there are new effective vaccines …

The global response: How cities and provinces around the globe tackled Covid-19 outbreaks in 2021

N Jain, IC Hung, H Kimura, YL Goh, W Jau… - The Lancet Regional …, 2022 - thelancet.com
Background Tackling the spread of COVID-19 remains a crucial part of ending the
pandemic. Its highly contagious nature and constant evolution coupled with a relative lack of …