The use of antibiotics has enabled the successful treatment of bacterial infections, saving the
lives and improving the health of many patients worldwide. However, the emergence and …

Neisseria gonorrhoeae infection is an important public health issue, with an annual global
incidence of 87 million. N. gonorrhoeae infection causes significant morbidity and can have …

In the modern era, the consumption of antibiotics represents a revolutionary weapon against
several infectious diseases, contributing to the saving of millions of lives worldwide …

The human vagina is a dynamic ecosystem in which homeostasis depends on mutually
beneficial interactions between the host and their microorganisms. However, the vaginal …

Rationale for review International travel facilitates the spread of drug-resistant infections,
including sexually transmitted infections (STIs). In 2016, the World Health Organization …

Pelvic inflammatory disease (PID) is an infection of the female upper genital tract that is
typically polymicrobial with classic core involvement of Neisseria gonorrhoeae and/or …

Background Gonorrhea incidence is increasing rapidly in many countries, while antibiotic
resistance is making treatment more difficult. Combined with evidence that two …

The surface transferrin receptor proteins from Neisseria gonorrhoeae have been recognized
as ideal vaccine targets due to their critical role in survival in the human male genitourinary …

Objective To provide an in-depth systematic assessment of the global epidemiology of
gonorrhoea infection in infertile populations. Methods A systematic literature review was …

An effective prophylactic vaccine for prevention of Neisseria gonorrhoeae infection would
have a major impact on sexual and reproductive health worldwide. Interest in developing …