[HTML][HTML] Fatty acids consumption: the role metabolic aspects involved in obesity and its associated disorders

P Silva Figueiredo, A Carla Inada, G Marcelino… - Nutrients, 2017 - mdpi.com
Obesity and its associated disorders, such as insulin resistance, dyslipidemia, metabolic
inflammation, dysbiosis, and non-alcoholic hepatic steatosis, are involved in several …

Do patients benefit from omega-3 fatty acids?

SCR Sherratt, RP Mason, P Libby… - Cardiovascular …, 2023 - academic.oup.com
Abstract Omega-3 fatty acids (O3FAs) possess beneficial properties for cardiovascular (CV)
health and elevated O3FA levels are associated with lower incident risk for CV disease …

Suppression of ACADM-mediated fatty acid oxidation promotes hepatocellular carcinoma via aberrant CAV1/SREBP1 signaling

APY Ma, CLS Yeung, SK Tey, X Mao, SWK Wong… - Cancer research, 2021 - AACR
Lipid accumulation exacerbates tumor development, as it fuels the proliferative growth of
cancer cells. The role of medium-chain acyl-CoA dehydrogenase (ACADM), an enzyme that …

[HTML][HTML] The effects of omega 3 and omega 6 fatty acids on glucose metabolism: An updated review

F Egalini, O Guardamagna, G Gaggero, E Varaldo… - Nutrients, 2023 - mdpi.com
Massive changes have occurred in our diet. A growing consumption of vegetal oils rich in
omega-6 (ω-6) and a depletion of omega-3 (ω-3) fatty acids (FAs) in our food has led to an …

Eicosapentaenoic and docosahexaenoic acids differentially alter gut microbiome and reverse high‐fat diet–induced insulin resistance

P Zhuang, Y Zhang, Q Shou, H Li, Y Zhu… - Molecular Nutrition & …, 2020 - Wiley Online Library
Scope To assess the individual effects of dietary eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA) on insulin resistance (IR), gut microbiome, and gut …

[HTML][HTML] A biological rationale for the disparate effects of omega-3 fatty acids on cardiovascular disease outcomes

SCR Sherratt, P Libby, DL Bhatt, RP Mason - … , Leukotrienes and Essential …, 2022 - Elsevier
The omega-3 fatty acids (n3-FAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid
(DHA) rapidly incorporate into cell membranes where they modulate signal transduction …

Resolvin E1 derived from eicosapentaenoic acid prevents hyperinsulinemia and hyperglycemia in a host genetic manner

A Pal, AE Al‐Shaer, W Guesdon, MJ Torres… - The FASEB …, 2020 - Wiley Online Library
Eicosapentaenoic acid (EPA) has garnered attention after the success of the REDUCE‐IT
trial, which contradicted previous conclusions on EPA for cardiovascular disease risk. Here …

[HTML][HTML] Eicosapentaenoic and docosahexaenoic acids attenuate hyperglycemia through the microbiome-gut-organs axis in db/db mice

P Zhuang, H Li, W Jia, Q Shou, Y Zhu, L Mao, W Wang… - Microbiome, 2021 - Springer
Background Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been
suggested to prevent the development of metabolic disorders. However, their individual role …

[HTML][HTML] Mechanisms by which dietary fatty acids regulate mitochondrial structure-function in health and disease

EM Sullivan, ER Pennington, WD Green, MA Beck… - Advances in …, 2018 - Elsevier
Mitochondria are the energy-producing organelles within a cell. Furthermore, mitochondria
have a role in maintaining cellular homeostasis and proper calcium concentrations, building …

[HTML][HTML] Eicosapentaenoic acid shows anti-inflammatory effect via GPR120 in 3T3-L1 adipocytes and attenuates adipose tissue inflammation in diet-induced obese …

H Yamada, T Umemoto, M Kakei, S Momomura… - Nutrition & …, 2017 - Springer
Background Saturated fatty acids have been shown to cause insulin resistance and low-
grade chronic inflammation, whereas unsaturated fatty acids suppress inflammation via G …