Hypoxia, a low O2 tension, is a fundamental feature that occurs in physiological events as
well as pathophysiological conditions, especially mentioned for its role in the mechanism of …

Mesenchymal stem/stromal cells (MSCs)‐based therapy brings the reassuring capability to
regenerative medicine through their self‐renewal and multilineage potency. Also, they …

Background Bone metastasis is the leading cause of death in patients with prostate cancer
(PCa) and currently has no effective treatment. Disseminated tumor cells in bone marrow …

Bone damage may be triggered by a variety of factors, and the damaged area often requires
a bone graft. Bone tissue engineering can serve as an alternative strategy for repairing large …

Hypoxia preconditioning enhances the paracrine abilities of mesenchymal stem cells
(MSCs) for vascular regeneration and tissue healing. Implantation of hypoxia‐induced …

Intervertebral disc degeneration (IVDD) is a main cause of lower back pain, leading to
psychological and economic burdens to patients. Physical therapy only delays pain in …

Background Skeletal muscle regeneration is a complex process regulated by many
cytokines and growth factors. Among the important signaling pathways regulating the …

Dental pulp angiogenesis is a committed step in pulp regeneration therapy, and exosomes
provide a new cell-free choice for tissue regeneration. This study revealed the underlying …

Fusion among different cell populations represents a rare process that is mediated by both
intrinsic and extracellular events. Cellular hybrid formation is relayed by orchestrating tightly …

Osteoarthritis (OA) is the most common age-related degenerative joint disease mainly
characterized by the destruction of articular cartilage. Owing to its native avascular property …