Multiple sclerosis (MS) is a demyelinating inflammatory disorder of the central nervous
system (CNS), which involves autoimmune responses to myelin antigens. Studies in …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) in which the immune system damages the protective insulation surrounding the nerve …

The mammalian brain contains neurogenic niches that comprise neural stem cells and other
cell types. Neurogenic niches become less functional with age, but how they change during …

Neuroinflammation is involved in several neurodegenerative disorders and emerging
evidence indicates that it constitutes a critical process that is required for the progression of …

Autoreactive T cells are thought to play an essential role in the pathogenesis of multiple
sclerosis (MS). We examined the stimulatory effect of human myelin basic protein (MBP) on …

The vast majority of studies regarding the immune basis of MS (and its animal model, EAE)
have largely focused on CD4+ T-cells as mediators and regulators of disease. Interestingly …

Cognitive impairment is one of the most frequent symptoms in patients with multiple
sclerosis (MS) but its underlying mechanisms are poorly understood. A number of …

Multiple Sclerosis (MS) is a chronic inflammatory neurodegenerative disease of central
nervous system (CNS). Although the main cause of MS is not clear, studies suggest that MS …

Gap junctions facilitate direct cytoplasmic communication between neighboring cells,
facilitating the transfer of small molecular weight molecules involved in cell signaling and …

Multiple sclerosis (MS) is a debilitating disease characterized by demyelination of the central
nervous system (CNS), resulting in widespread formation of white matter lesions (WMLs) …