The blood-brain barrier (BBB) constitutes a microvascular network responsible for excluding
most drugs from the brain. Treatment of brain tumors is limited by the impermeability of the …

Polyelectrolyte complexes (PECs) as safe drug delivery carriers, are spontaneously formed
by mixing the oppositely charged polyelectrolyte solutions in water without using organic …

The blood–brain barrier (BBB) acts as a barrier to prevent the central nervous system (CNS)
from damage by substances that originate from the blood circulation. The BBB limits drug …

Diabetic and anemia-associated diabetic wounds increase the considerable morbidity and
mortality in people, as reported by clinical studies. However, no anemia-associated diabetic …

Abstract Chitosan (CS)-based pH-sensitive nanocomposites were fabricated for the targeted
delivery of doxorubicin (DOX) to osteosarcoma cells. To prepare the nanocomposite, CS …

Organic and inorganic nanoparticles (NPs) have attracted significant attention due to their
unique physico-chemical properties, which have paved the way for their application in …

The poor prognosis and rapid recurrence of glioblastoma (GB) are associated to its fast-
growing process and invasive nature, which make difficult the complete removal of the …

Glioblastoma (GBM) is an aggressive, fatal and malignant primary brain tumor. Despite the
current standard treatment for glioblastoma patients including neurosurgical resection …

Designing novel systems for efficient cancer treatment and improving the quality of life for
patients is a prime requirement in the healthcare sector. In this regard, theranostics have …

The efficacy of different modalities of treating breast cancer is inhibited by several limitations
such as off-targeted drug distribution, rapid drug clearance, and drug resistance. To …