This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

Plasticity in animal behaviour relies on the ability to integrate external and internal cues from
the changing environment and hence modulate activity in synaptic circuits of the brain. This …

We define the chemoconnectome (CCT) as the entire set of neurotransmitters,
neuromodulators, neuropeptides, and their receptors underlying chemotransmission in an …

The insulin/insulin-like growth factor signaling pathway is an evolutionary conserved
pathway across metazoans and is required for development, metabolism and behavior. This …

Circadian clocks regulate much of behavior and physiology, but the mechanisms by which
they do so remain poorly understood. While cyclic gene expression is thought to underlie …

Proper regulation of sleep-wake behavior and feeding is essential for organismal health and
survival. While previous studies have isolated discrete neural loci and substrates important …

A prominent idea emerging from the study of sleep is that this key behavioural state is
regulated in a complex fashion by ecologically and physiologically relevant environmental …

Insulin‐like peptides (ILPs) belong to the insulin superfamily and act as hormones,
neuromediators, and growth factors during the post‐embryonic life‐cycle stages of insects …

Sleep is a biological enigma that has raised numerous questions about the inner workings
of the brain. The fundamental question of why our nervous systems have evolved to require …

Understanding evolutionary responses to variation in temperature and precipitation across
species ranges is of fundamental interest given ongoing climate change. The importance of …