Characterization of the interaction between protein Snu13p/15.5 K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly
The yeast Snu13p protein and its 15.5 K human homolog both bind U4 snRNA and box C/D
snoRNAs. They also bind the Rsa1p/NUFIP assembly factor, proposed to scaffold immature …
snoRNAs. They also bind the Rsa1p/NUFIP assembly factor, proposed to scaffold immature …
SUMOylation-and GAR1-dependent regulation of dyskerin nuclear and subnuclear localization
DE MacNeil, P Lambert-Lanteigne, J Qin… - … and Cellular Biology, 2021 - Taylor & Francis
The nuclear and subnuclear compartmentalization of the telomerase-associated protein and
H/ACA ribonucleoprotein component dyskerin is an important although incompletely …
H/ACA ribonucleoprotein component dyskerin is an important although incompletely …
[HTML][HTML] RNA mimicry by the fap7 adenylate kinase in ribosome biogenesis
During biogenesis of the 40S and 60S ribosomal subunits, the pre-40S particles are
exported to the cytoplasm prior to final cleavage of the 20S pre-rRNA to mature 18S rRNA …
exported to the cytoplasm prior to final cleavage of the 20S pre-rRNA to mature 18S rRNA …
The C-terminal extension of dyskerin is a dyskeratosis congenita mutational hotspot that modulates interaction with telomerase RNA and subcellular localization
J Qin, A Garus, C Autexier - Human Molecular Genetics, 2024 - academic.oup.com
Dyskerin is a component of the human telomerase complex and is involved in stabilizing the
human telomerase RNA (hTR). Many mutations in the DKC1 gene encoding dyskerin are …
human telomerase RNA (hTR). Many mutations in the DKC1 gene encoding dyskerin are …
[HTML][HTML] Placeholder factors in ribosome biogenesis: please, pave my way
FJ Espinar-Marchena, R Babiano, J Cruz - Microbial Cell, 2017 - ncbi.nlm.nih.gov
The synthesis of cytoplasmic eukaryotic ribosomes is an extraordinarily energy-demanding
cellular activity that occurs progressively from the nucleolus to the cytoplasm. In the …
cellular activity that occurs progressively from the nucleolus to the cytoplasm. In the …
[HTML][HTML] Deletion of 3p13-14 locus spanning FOXP1 to SHQ1 cooperates with PTEN loss in prostate oncogenesis
H Hieronymus, PJ Iaquinta, J Wongvipat… - Nature …, 2017 - nature.com
A multigenic locus at 3p13-14, spanning FOXP1 to SHQ1, is commonly deleted in prostate
cancer and lost broadly in a range of cancers but has unknown significance to oncogenesis …
cancer and lost broadly in a range of cancers but has unknown significance to oncogenesis …
[HTML][HTML] snR30/U17 small nucleolar ribonucleoprotein: a critical player during ribosome biogenesis
TJ Vos, U Kothe - Cells, 2020 - mdpi.com
The small nucleolar RNA snR30 (U17 in humans) plays a unique role during ribosome
synthesis. Unlike most members of the H/ACA class of guide RNAs, the small nucleolar …
synthesis. Unlike most members of the H/ACA class of guide RNAs, the small nucleolar …
Regulation of human telomerase RNA biogenesis and localization
J Qin, C Autexier - RNA biology, 2021 - Taylor & Francis
Maintenance of telomeres is essential for genome integrity and replicative capacity in
eukaryotic cells. Telomerase, the ribonucleoprotein complex that catalyses telomere …
eukaryotic cells. Telomerase, the ribonucleoprotein complex that catalyses telomere …
[HTML][HTML] Post-transcriptional and post-translational modifications in telomerase biogenesis and recruitment to telomeres
N Shepelev, O Dontsova, M Rubtsova - International Journal of Molecular …, 2023 - mdpi.com
Telomere length is associated with the proliferative potential of cells. Telomerase is an
enzyme that elongates telomeres throughout the entire lifespan of an organism in stem cells …
enzyme that elongates telomeres throughout the entire lifespan of an organism in stem cells …
[HTML][HTML] SnoRNAs: Exploring Their Implication in Human Diseases
W Chauhan, SJ Sudharshan, S Kafle… - International Journal of …, 2024 - mdpi.com
Small nucleolar RNAs (snoRNAs) are earning increasing attention from research
communities due to their critical role in the post-transcriptional modification of various RNAs …
communities due to their critical role in the post-transcriptional modification of various RNAs …