Animal models in the pharmacokinetic/pharmacodynamic evaluation of antimicrobial agents

M Zhao, AJ Lepak, DR Andes - Bioorganic & medicinal chemistry, 2016 - Elsevier
Animal infection models in the pharmacokinetic/pharmacodynamic (PK/PD) evaluation of
antimicrobial therapy serve an important role in preclinical assessments of new antibiotics …

Treatment of Enterococcus faecalis Infective Endocarditis: A Continuing Challenge

L Herrera-Hidalgo, B Fernández-Rubio… - Antibiotics, 2023 - mdpi.com
Today, Enterococcus faecalis is one of the main causes of infective endocarditis in the world,
generally affecting an elderly and fragile population, with a high mortality rate. Enterococci …

Ampicillin Plus Ceftriaxone Is as Effective as Ampicillin Plus Gentamicin for Treating Enterococcus faecalis Infective Endocarditis

N Fernández-Hidalgo, B Almirante… - Clinical infectious …, 2013 - academic.oup.com
Background. The aim of this study was to compare the effectiveness of the ampicillin plus
ceftriaxone (AC) and ampicillin plus gentamicin (AG) combinations for treating Enterococcus …

Dental disease and periprosthetic joint infection

H Young, J Hirsh, EM Hammerberg, CS Price - JBJS, 2014 - journals.lww.com
Dental Disease and Periprosthetic Joint Infection : JBJS Dental Disease and Periprosthetic
Joint Infection : JBJS JBJS Journal Case Connector Reviews JBJS.org Surgical Techniques …

Enterococcus faecalis infective endocarditis: focus on clinical aspects

A Dahl, NE Bruun - Expert review of cardiovascular therapy, 2013 - Taylor & Francis
Enterococcus faecalis infective endocarditis (IE) is a disease of increasing importance, with
more patients infected, increasing frequency of health-care associated infections and …

Enterococcal endocarditis revisited

JM Pericás, Y Zboromyrska, C Cervera… - Future …, 2015 - Taylor & Francis
The Enterococcus species is the third main cause of infective endocarditis (IE) worldwide,
and it is gaining relevance, especially among healthcare-associated cases. Patients with …

Multilocus sequence typing and antimicrobial resistance in Enterococcus faecium isolates from fresh produce

MJG Burgos, MCL Aguayo, RP Pulido, A Gálvez… - Antonie Van …, 2014 - Springer
The purpose of the present study was to determine the relatedness of Enterococcus faecium
isolates from fresh produce to E. faecium strains from other sources by using multi-locus …

Low efficacy of tobramycin in experimental Staphylococcus aureus endocarditis

CJ Lerche, LJ Christophersen, H Trøstrup… - European Journal of …, 2015 - Springer
The empiric treatment of infective endocarditis (IE) varies widely and, in some places, a
regimen of penicillin in combination with an aminoglycoside is administered. The increasing …

The challenge of curbing aminoglycoside resistance: can antimicrobial stewardship programs play a critical role?

V Pitiriga, E Dimitroulia, G Saroglou… - Expert review of anti …, 2017 - Taylor & Francis
Introduction: Aminoglycosides are useful antimicrobials, primarily for serious infections
involving aerobic gram-negative pathogens. The inevitable increase in aminoglycoside …

Endocarditis caused by resistant Enterococcus: an overview

K Reyes, M Zervos - Current infectious disease reports, 2013 - Springer
Enteroccocal infective endocarditis is a major challenge to clinicians. There are an
increasing number of reports of nosocomial acquisition and multidrug-resistant strains …